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NCT02606292 · ClinicalTrials.gov registry record · Early Phase 1
Photoacoustic Endoscopy of Barrett's Esophagus
A Early Phase 1 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 8
- Enrollment target
NCT02606292: Completed Early Phase 1 study, sponsored by Washington University School of Medicine.
NCT02606292 is a Early Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 8 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02606292, a Early Phase 1 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
Endoscopy is an important technique in medicine to diagnose internal organs. Video endoscopy has been the most common technique providing clear, real time video images of organs' surfaces. However, this technique only images the surface and cannot effectively diagnose diseased tissues that develop in endothelial tissues. Endoscopic ultrasound (EUS) has been developed to overcome this limitation, and it is widely utilized in diagnosing GI diseases. This technique can image very deep areas of organs, up to several centimeters; however, it suffers from speckle artifacts and cannot adequately provide early diagnosis of tissue abnormalities that do not show mechanical properties that differ significantly from those of normal tissues. The investigators propose that photoacoustic endoscopy (PAE), an endoscopic embodiment of the rapidly growing photoacoustic tomography (PAT) technology, can fulfill the aforementioned need.
Primary Outcome
-The investigators will image a series of human esophagi in patients with an established diagnosis of Barrett's esophagus with/without dysplasia to fine-tune the PA imaging system. The investigators will assess the agreement between the PA imaging system and the standard clinical practice of four-quadrant esophageal biopsy previously performed in this cohort of patients as part of his/her active surveillance program.
Interventions
- PROCEDURE Photoacoustic endoscopy
- PROCEDURE Endoscopic ultrasound (standard of care)
- PROCEDURE Endoscopic surgery (standard of care)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2014-08 |
| Est. Completion | 2016-08 |
| Phase | Early Phase 1 |
What the finished NCT02606292 record still lists
NCT02606292 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 3 interventions - of which Photoacoustic endoscopy is the first listed.
NCT02606292 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02606292 about?
NCT02606292 is a clinical study titled "Photoacoustic Endoscopy of Barrett's Esophagus". Endoscopy is an important technique in medicine to diagnose internal organs. Video endoscopy has been the most common technique providing clear, real time video images of organs' surfaces. However, this technique only images the surface and cannot effectively diagnose diseased tissues that develop i...
What is the current status of trial NCT02606292?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 8 participants. The study started on 2014-08. Estimated completion is 2016-08.
What interventions are being tested in trial NCT02606292?
The interventions under investigation include: Photoacoustic endoscopy (PROCEDURE), Endoscopic ultrasound (standard of care) (PROCEDURE), Endoscopic surgery (standard of care) (PROCEDURE).
Who is sponsoring clinical trial NCT02606292?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02606292's enrollment target sits among peer trials
8 1782nd of 2000 higher than 176 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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