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NCT02598349 · ClinicalTrials.gov registry record · Phase 2

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

A Phase 2 study of Pancreatic Cancer, sponsored by Proton Collaborative Group.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
4
Study locations

NCT02598349 is a Phase 2 study of Pancreatic Cancer that is actively recruiting participants, run by Proton Collaborative Group. The registered enrollment target is 60 participants, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (85% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT02598349, a Phase 2 study of Pancreatic Cancer, is actively recruiting participants, sponsored by Proton Collaborative Group.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
4
Study locations

Study Summary

The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline resectable" disease treated with preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to resectability. It may be argued that intensification of local and regional therapy might 1.) Increase the share of patients able to undergo curative surgery and 2.) Improve the local disease control interval and extend survival for patients who remain unresectable. Therefore, the purpose of this research study is to determine if an increase in the number of surgical resection pancreatic adenocarcinoma is higher than historical data by using a combined treatment of proton radiation with capecitabine (oral chemotherapy).

Conditions Studied

Interventions

  • DRUG Capecitabine
  • PROCEDURE Surgical resection
  • RADIATION Proton Radiation

Study Locations (4)

Florida

  • University of Florida Proton Therapy Institute - Jacksonville

Illinois

  • Northwestern Medicine Chicago Proton Center - Warrenville

Michigan

  • McLaren Proton Therapy Center - Flint

Virginia

  • Inova Schar Cancer Institute - Fairfax

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2016-04
Est. Completion 2040-10
Phase Phase 2

Sponsor

Proton Collaborative Group

10 total trials

What the Registry Record Tells You About NCT02598349

The ClinicalTrials.gov registry entry for NCT02598349 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (85% lower). The listed sponsor is Proton Collaborative Group, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreatic Cancer appearing as the primary indexed condition, and to 3 interventions - of which Capecitabine is the first listed.

NCT02598349 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Florida, Illinois, Michigan.

Frequently Asked Questions

What is clinical trial NCT02598349 about?

NCT02598349 is a clinical study titled "Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas". The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline resectable" disease treated with preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to resec...

What is the current status of trial NCT02598349?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2016-04. Estimated completion is 2040-10.

What conditions does trial NCT02598349 study?

This clinical trial studies the following conditions: Pancreatic Cancer.

What interventions are being tested in trial NCT02598349?

The interventions under investigation include: Capecitabine (DRUG), Surgical resection (PROCEDURE), Proton Radiation (RADIATION).

Who is sponsoring clinical trial NCT02598349?

This trial is sponsored by Proton Collaborative Group, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02598349 being conducted?

This trial has 4 study locations across Florida, Illinois, Michigan, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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