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NCT02596776 · ClinicalTrials.gov registry record · Early Phase 1
Cold Induced Changes in White Adipose
A Early Phase 1 study, sponsored by Philip Kern.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 26
- Enrollment target
NCT02596776: Completed Early Phase 1 study, sponsored by Philip Kern.
NCT02596776 is a Early Phase 1 study that has completed, run by Philip Kern. The registered enrollment target is 26 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02596776, a Early Phase 1 study, has completed, sponsored by Philip Kern.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
An adaptation to a cold environment is a tendency to generate heat within our body. Some of this heat comes from our fat tissue. Although most fat tissue is "white fat", there are pockets deep within the body that are called "brown fat", which are specially adapted to burning fat and making heat. The investigator believes that our white fat, just underneath the surface of our skin, also has this property to burn fat and make heat, although not at the high level of brown fat. This study is to examine this fat-burning property of the white fat under the skin in response to seasons and to cold. Many such studies have been done in mice, but little has been done in humans. There are a number of factors, including age, weight, and medical history, that may make a person eligible or ineligible to participate in this study. Certain medications could make a person ineligible, but if these medications can be safely altered, the individual may become eligible.
Primary Outcome
Adipose biopsies will be performed
Interventions
- PROCEDURE Fat biopsy
- DRUG Propranolol and fat biopsy
- OTHER heavy water and fat biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2016-03 |
| Est. Completion | 2018-08-20 |
| Phase | Early Phase 1 |
What the finished NCT02596776 record still lists
NCT02596776 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% lower).
The record links to 0 conditions, and to 3 interventions - of which Fat biopsy is the first listed.
NCT02596776 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02596776 about?
NCT02596776 is a clinical study titled "Cold Induced Changes in White Adipose". An adaptation to a cold environment is a tendency to generate heat within our body. Some of this heat comes from our fat tissue. Although most fat tissue is "white fat", there are pockets deep within the body that are called "brown fat", which are specially adapted to burning fat and making heat. Th...
What is the current status of trial NCT02596776?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 26 participants. The study started on 2016-03. Estimated completion is 2018-08-20.
What interventions are being tested in trial NCT02596776?
The interventions under investigation include: Fat biopsy (PROCEDURE), Propranolol and fat biopsy (DRUG), heavy water and fat biopsy (OTHER).
Who is sponsoring clinical trial NCT02596776?
This trial is sponsored by Philip Kern, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02596776's enrollment target sits among peer trials
26 977th of 2000 higher than 1,001 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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