Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02589340 · ClinicalTrials.gov registry record · Phase 1
Buspirone, in Combination With Amantadine, for the Treatment of Levodopa-induced Dyskinesia
A Phase 1 study, sponsored by Oregon Health and Science University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
NCT02589340: Clinical Trial Phase 1 study, sponsored by Oregon Health and Science University.
NCT02589340 is a Phase 1 study that was terminated before completion, run by Oregon Health and Science University. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02589340, a Phase 1 study, was terminated before completion, sponsored by Oregon Health and Science University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
The primary objective of this study is to evaluate the efficacy of buspirone in combination with amantadine in reducing levodopa-induced dyskinesia (LID) in patients with Parkinson's disease (PD).
Primary Outcome
forceplate measurements of levodopa induced dyskinesia taken every 1/2 hour for 6 hours.
Interventions
- DRUG Placebo
- DRUG Buspirone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2016-01 |
| Est. Completion | 2021-02-23 |
| Phase | Phase 1 |
Why NCT02589340 stopped before completion
NCT02589340 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02589340 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02589340 about?
NCT02589340 is a clinical study titled "Buspirone, in Combination With Amantadine, for the Treatment of Levodopa-induced Dyskinesia". The primary objective of this study is to evaluate the efficacy of buspirone in combination with amantadine in reducing levodopa-induced dyskinesia (LID) in patients with Parkinson's disease (PD).
What is the current status of trial NCT02589340?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2016-01. Estimated completion is 2021-02-23.
What interventions are being tested in trial NCT02589340?
The interventions under investigation include: Placebo (DRUG), Buspirone (DRUG).
Who is sponsoring clinical trial NCT02589340?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02589340's enrollment target sits among peer trials
6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia