Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02581098 · ClinicalTrials.gov registry record
miR-200b & miR-21 in Diabetic Wounds
A clinical trial, sponsored by Indiana University.
- Completed
- Registry status
- 98
- Enrollment target
NCT02581098: Completed study, sponsored by Indiana University.
NCT02581098 is a clinical trial that has completed, run by Indiana University. The registered enrollment target is 98 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02581098 has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- 98 participants
- Enrollment target
Study Summary
This study aims to determine if elevated wound-edge endothelial miR-200b is a barrier to wound healing in diabetic patients and also to determine if ex vivo supplementation of miR-21 mimic and recombinant MFG-E8 resolve inflammation in wound macrophages isolated from NPWT sponges from diabetic wounds. This study will enroll 124 (60 in the miR-200b arm and 64 in the miR21 arm) Diabetic Wound patients who have wound tissue oxygenation adequate to support wound healing and will be in the study for 14 weeks that includes 4 study visits.
Primary Outcome
This study aims to determine if elevated wound-edge endothelial miR-200b and attenuated wound macrophage miR-21 levels are barriers to wound healing (closure) in diabetic wounds.
Interventions
- OTHER No interventions
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 98 participants |
| Start Date | 2015-08 |
| Est. Completion | 2023-06-26 |
What the finished NCT02581098 record still lists
NCT02581098 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 98 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which No interventions is the first listed.
NCT02581098 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02581098 about?
NCT02581098 is a clinical study titled "miR-200b & miR-21 in Diabetic Wounds". This study aims to determine if elevated wound-edge endothelial miR-200b is a barrier to wound healing in diabetic patients and also to determine if ex vivo supplementation of miR-21 mimic and recombinant MFG-E8 resolve inflammation in wound macrophages isolated from NPWT sponges from diabetic wound...
What is the current status of trial NCT02581098?
This trial is currently completed. The enrollment target is 98 participants. The study started on 2015-08. Estimated completion is 2023-06-26.
What interventions are being tested in trial NCT02581098?
The interventions under investigation include: No interventions (OTHER).
Who is sponsoring clinical trial NCT02581098?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02926729 · 98 participants · NA
Real-Time Assessment Of Breast Cancer Lumpectomy Specimen Margins With Nonlinear Microscopy
- NCT03382977 · 98 participants · Phase 1
Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects
- NCT04577014 · 98 participants · Phase 1
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
- NCT04817618 · 98 participants · Phase 3
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia