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NCT02579460 · ClinicalTrials.gov registry record · NA
Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition
A NA study, sponsored by Dallas VA Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT02579460 is a NA study that has completed, run by Dallas VA Medical Center. The registered enrollment target is 15 participants.
The verdict
NCT02579460, a NA study, has completed, sponsored by Dallas VA Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
The purpose of this study is to elucidate mechanisms whereby oxidative stress induced by acute reflux esophagitis: 1) activates p38 to regulate proteins that control the G1/S cell cycle checkpoint, and 2) activates HIFs (hypoxia inducible factors) to cause autocrine VEGF (vascular endothelial growth factor) signaling that triggers the EMT (epithelial-mesenchymal-transition) program in Barrett's esophagus.
Interventions
- OTHER Cessation of Acid Suppressing Medications
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2015-11 |
| Est. Completion | 2017-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02579460
The ClinicalTrials.gov registry entry for NCT02579460 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dallas VA Medical Center, which has 20 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Cessation of Acid Suppressing Medications is the first listed.
NCT02579460 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02579460 about?
NCT02579460 is a clinical study titled "Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition". The purpose of this study is to elucidate mechanisms whereby oxidative stress induced by acute reflux esophagitis: 1) activates p38 to regulate proteins that control the G1/S cell cycle checkpoint, and 2) activates HIFs (hypoxia inducible factors) to cause autocrine VEGF (vascular endothelial growth...
What is the current status of trial NCT02579460?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2015-11. Estimated completion is 2017-11.
What interventions are being tested in trial NCT02579460?
The interventions under investigation include: Cessation of Acid Suppressing Medications (OTHER).
Who is sponsoring clinical trial NCT02579460?
This trial is sponsored by Dallas VA Medical Center, which has 20 total clinical trials registered on ClinicalTrials.gov.
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