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NCT02579161 · ClinicalTrials.gov registry record · Phase 3

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

A Phase 3 study, sponsored by Northwell Health.

Completed
Registry status
Phase 3
Development phase
98
Enrollment target

NCT02579161: Completed Phase 3 study, sponsored by Northwell Health.

NCT02579161 is a Phase 3 study that has completed, run by Northwell Health. The registered enrollment target is 98 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02579161, a Phase 3 study, has completed, sponsored by Northwell Health.

COMPLETED
Registry status
Phase 3
Development phase
98 participants
Enrollment target

Study Summary

The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce hospital costs and prevent the further propagation of resistant microbes.

Primary Outcome

Compare the rate of infectious complications following a single-dose of peri-operative protocol (antibiotics for 24 hours as recommended by the American Urological Association Guidelines) with a short-course protocol (antibiotics continued until any external catheters such as nephrostomy tubes are removed) following percutaneous nephrolithotomy. Complication rate differences, primarily infectious complications such as fever, sepsis, systemic inflammatory response.

Interventions

  • DRUG Clindamycin
  • DRUG cephalosporins
  • DRUG Fluoroquinolones
  • DRUG Ampicillin/Gentamicin

Trial Details

FieldValue
Enrollment Target 98 participants
Start Date 2014-09
Est. Completion 2018-12
Phase Phase 3
Northwell Health

370 total trials

What the finished NCT02579161 record still lists

NCT02579161 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 98 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 4 interventions - of which Clindamycin is the first listed.

NCT02579161 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02579161 about?

NCT02579161 is a clinical study titled "Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy". The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce hospital costs and prevent the further propagation of resistant microbes...

What is the current status of trial NCT02579161?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 98 participants. The study started on 2014-09. Estimated completion is 2018-12.

What interventions are being tested in trial NCT02579161?

The interventions under investigation include: Clindamycin (DRUG), cephalosporins (DRUG), Fluoroquinolones (DRUG), Ampicillin/Gentamicin (DRUG).

Who is sponsoring clinical trial NCT02579161?

This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02579161's enrollment target sits among peer trials

98 1714th of 2000 higher than 283 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02579161, the US trial registry maintained by the National Library of Medicine. NCT02579161 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.