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NCT02578108 · ClinicalTrials.gov registry record · NA

Diagnostic Genicular Nerve Block Prior to Radiofrequency Ablation for Knee Osteoarthritis Pain

A NA study, sponsored by Northwestern University.

Completed
Registry status
NA
Development phase
63
Enrollment target

NCT02578108: Completed NA study, sponsored by Northwestern University.

NCT02578108 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 63 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02578108, a NA study, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
NA
Development phase
63 participants
Enrollment target

Study Summary

Chronic painful knee OA is a major cause of disability in older adults. In patients whose symptoms are refractory to conservative management but who do not wish to undergo TKA or, alternatively, are not operative candidates, genicular nerve RFA represents a promising treatment option. Investigators will determine if patients with chronic painful knee osteoarthritis experience meaningful and long-term improvement in pain, function, and analgesic use, as well as prevention of TKA after RFA of the genicular nerves. Investigators will also determine whether zero versus one set of diagnostic genicular nerve blocks Answering these questions will help determine if genicular nerve RFA is indeed a worthwhile treatment for chronic painful knee OA. Additionally, this will help determine the optimal diagnostic protocol for patient selection for this procedure, which has implications for improving treatment success rates, preventing unnecessary procedures, and decreasing healthcare cost savings.

Primary Outcome

Outcomes will be compared between those who received a set of diagnostic blocks and those who did not receive a set of diagnostic blocks (arm 1 vs. arm 2)

Interventions

  • PROCEDURE genicular nerve diagnostic block with lidocaine (local anesthetic)
  • PROCEDURE genicular nerve radiofrequency ablation

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2015-10
Est. Completion 2018-09
Phase NA
Northwestern University

1,209 total trials

What the finished NCT02578108 record still lists

NCT02578108 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 63 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which genicular nerve diagnostic block with lidocaine (local anesthetic) is the first listed.

NCT02578108 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02578108 about?

NCT02578108 is a clinical study titled "Diagnostic Genicular Nerve Block Prior to Radiofrequency Ablation for Knee Osteoarthritis Pain". Chronic painful knee OA is a major cause of disability in older adults. In patients whose symptoms are refractory to conservative management but who do not wish to undergo TKA or, alternatively, are not operative candidates, genicular nerve RFA represents a promising treatment option. Investigators...

What is the current status of trial NCT02578108?

This trial is currently completed. It is a NA study. The enrollment target is 63 participants. The study started on 2015-10. Estimated completion is 2018-09.

What interventions are being tested in trial NCT02578108?

The interventions under investigation include: genicular nerve diagnostic block with lidocaine (local anesthetic) (PROCEDURE), genicular nerve radiofrequency ablation (PROCEDURE).

Who is sponsoring clinical trial NCT02578108?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02578108's enrollment target sits among peer trials

63 1157th of 2000 higher than 844 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02578108, the US trial registry maintained by the National Library of Medicine. NCT02578108 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.