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NCT02577250 · ClinicalTrials.gov registry record · Phase 1
Ketamine Infusions for PTSD and Treatment-Resistant Depression
A Phase 1 study, sponsored by Minneapolis Veterans Affairs Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT02577250: Completed Phase 1 study, sponsored by Minneapolis Veterans Affairs Medical Center.
NCT02577250 is a Phase 1 study that has completed, run by Minneapolis Veterans Affairs Medical Center. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02577250, a Phase 1 study, has completed, sponsored by Minneapolis Veterans Affairs Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning. Veterans with both depression and PTSD have been shown to be at much higher risk of suicide than individuals with only one of these disorders. Ketamine has been shown to have rapid antidepressant effects and also therapeutic action over PTSD symptoms. The purpose of this study is to see whether ketamine, when given as repeated infusions, can produce quick and sustained improvement in depression and PTSD symptoms for individuals who have not had their symptoms effectively treated by current treatments.
Interventions
- DRUG Ketamine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2015-05 |
| Est. Completion | 2016-07 |
| Phase | Phase 1 |
What the finished NCT02577250 record still lists
NCT02577250 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which Ketamine is the first listed.
NCT02577250 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02577250 about?
NCT02577250 is a clinical study titled "Ketamine Infusions for PTSD and Treatment-Resistant Depression". The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning. Veterans with both depression and PTSD have been shown to be at much higher risk of suicide t...
What is the current status of trial NCT02577250?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2015-05. Estimated completion is 2016-07.
What interventions are being tested in trial NCT02577250?
The interventions under investigation include: Ketamine (DRUG).
Who is sponsoring clinical trial NCT02577250?
This trial is sponsored by Minneapolis Veterans Affairs Medical Center, which has 28 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02577250's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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