Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02573740 · ClinicalTrials.gov registry record · Phase 1

Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment

A Phase 1 study, sponsored by AbbVie.

Terminated
Registry status
Phase 1
Development phase
8
Enrollment target

NCT02573740: Clinical Trial Phase 1 study, sponsored by AbbVie.

NCT02573740 is a Phase 1 study that was terminated before completion, run by AbbVie. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02573740, a Phase 1 study, was terminated before completion, sponsored by AbbVie.

TERMINATED
Registry status
Phase 1
Development phase
8 participants
Enrollment target

Study Summary

This is a Phase 1, multicenter, randomized, double-blind, placebo-controlled, multiple dose study of ABT-957 in participants with mild Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) due to AD.

Interventions

  • OTHER Placebo
  • DRUG ABT-957

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2015-12
Est. Completion 2016-06
Phase Phase 1
AbbVie

526 total trials

Why NCT02573740 stopped before completion

NCT02573740 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02573740 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02573740 about?

NCT02573740 is a clinical study titled "Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment". This is a Phase 1, multicenter, randomized, double-blind, placebo-controlled, multiple dose study of ABT-957 in participants with mild Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) due to AD.

What is the current status of trial NCT02573740?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2015-12. Estimated completion is 2016-06.

What interventions are being tested in trial NCT02573740?

The interventions under investigation include: Placebo (OTHER), ABT-957 (DRUG).

Who is sponsoring clinical trial NCT02573740?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02573740's enrollment target sits among peer trials

8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02573740, the US trial registry maintained by the National Library of Medicine. NCT02573740 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.