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NCT02570503 · ClinicalTrials.gov registry record · Phase 4

Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty

A Phase 4 study, sponsored by Virginia Commonwealth University.

Terminated
Registry status
Phase 4
Development phase
64
Enrollment target

NCT02570503 is a Phase 4 study that was terminated before completion, run by Virginia Commonwealth University. The registered enrollment target is 64 participants.

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The verdict

NCT02570503, a Phase 4 study, was terminated before completion, sponsored by Virginia Commonwealth University.

TERMINATED
Registry status
Phase 4
Development phase
64 participants
Enrollment target

Study Summary

This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels. The injection is a combination of various medications which are thought to reduce pain levels. Approximately 128 patients will participate in this study, half of the patients will receive this injection during surgery and the other half will receive a saline (salt water) injection. Pain scores after the surgery will be compared between the two groups. All patients will also receive a long-acting (24 hours) morphine injection during surgery. The hypothesis is that those participants receiving intrathecal Duramorph and local periarticular injections will have improved pain scores and reduced narcotic use when compared with intrathecal Duramorph alone at 48 hours postoperatively.

Interventions

  • DRUG Ketorolac
  • DRUG Epinephrine
  • DRUG Ropivacaine
  • DRUG 0.9% sodium chloride
  • DRUG Clonidine

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2015-10
Est. Completion 2021-02-11
Phase Phase 4

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT02570503

The ClinicalTrials.gov registry entry for NCT02570503 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 64 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Ketorolac is the first listed.

NCT02570503 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02570503 about?

NCT02570503 is a clinical study titled "Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty". This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels. The injection is a combination of various medications which are thought to reduce pain levels. Approximately 128 patients...

What is the current status of trial NCT02570503?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 64 participants. The study started on 2015-10. Estimated completion is 2021-02-11.

What interventions are being tested in trial NCT02570503?

The interventions under investigation include: Ketorolac (DRUG), Epinephrine (DRUG), Ropivacaine (DRUG), 0.9% sodium chloride (DRUG), Clonidine (DRUG).

Who is sponsoring clinical trial NCT02570503?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.