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NCT02565498 · ClinicalTrials.gov registry record · Phase 3
Preoperative vs Postoperative IMRT for Extremity/Truncal STS
A Phase 3 study of Adult Soft Tissue Sarcoma, sponsored by Mount Sinai Hospital, Canada.
- Active
- Registry status
- Phase 3
- Development phase
- 210
- Enrollment target
- 8
- Study locations
NCT02565498: Active Phase 3 study of Adult Soft Tissue Sarcoma, sponsored by Mount Sinai Hospital, Canada.
NCT02565498 is a Phase 3 study of Adult Soft Tissue Sarcoma that is active but no longer recruiting, run by Mount Sinai Hospital, Canada. The registered enrollment target is 210 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower). The trial reports 8 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02565498, a Phase 3 study of Adult Soft Tissue Sarcoma, is active but no longer recruiting, sponsored by Mount Sinai Hospital, Canada.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 210 participants
- Enrollment target
- 8
- Study locations
Study Summary
This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results in similar short-term wound healing complications as surgery followed by postoperative IGRT in patients with extremity or truncal soft tissue sarcoma. Half of the patients will receive preoperative radiotherapy, half will receive postoperative radiotherapy.
Primary Outcome
* Secondary operations required for wound treatment (debridement, secondary closure procedures such as rotationplasty, free flaps or skin grafts); * Readmission to hospital for wound care; * Invasive procedures required for wound care (drainage of hematoma, seroma or infected wound collection); * Deep wound packing required at any time (deep packing defined as packing deep to dermis in an area of dehisced wound) to an area of the wound measuring at least 2 cm in length; * Prolonged dressing chan
Conditions Studied
Interventions
- RADIATION Preoperative intensity modulated radiation therapy
- RADIATION Postoperative intensity modulated radiation therapy
Study Locations (8)
Ontario
- The Ottawa Hospital Cancer Centre - Ottawa
- Mount Sinai Hospital - Toronto
- Princess Margaret Cancer Centre - Toronto
Massachusetts
- Dana Farber Cancer Institute - Boston
Ohio
- Cleveland Clinic Taussig Cancer Institute - Cleveland
Oregon
- Oregon Health & Science University - Portland
Other
- Cliniques Universitaires Saint-Luc - Brussels
Quebec
- Hopital Maisonneuve-Rosemont - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2016-06 |
| Est. Completion | 2029-05 |
| Phase | Phase 3 |
What the registry record for NCT02565498 still lists
NCT02565498 is an interventional study that assigns participants to a tested intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower).
The record links to 1 condition, with Adult Soft Tissue Sarcoma appearing as the primary indexed condition, and to 2 interventions - of which Preoperative intensity modulated radiation therapy is the first listed.
NCT02565498 lists 8 locations in 6 states (Ontario, Massachusetts, Ohio).
Frequently Asked Questions
What is clinical trial NCT02565498 about?
NCT02565498 is a clinical study titled "Preoperative vs Postoperative IMRT for Extremity/Truncal STS". This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results in similar short-term wound healing complications as surgery followed by postoperative IGRT in patients with extremity or...
What is the current status of trial NCT02565498?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 210 participants. The study started on 2016-06. Estimated completion is 2029-05.
What conditions does trial NCT02565498 study?
This clinical trial studies the following conditions: Adult Soft Tissue Sarcoma.
What interventions are being tested in trial NCT02565498?
The interventions under investigation include: Preoperative intensity modulated radiation therapy (RADIATION), Postoperative intensity modulated radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT02565498?
This trial is sponsored by Mount Sinai Hospital, Canada, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02565498 being conducted?
This trial has 8 study locations across Massachusetts, Ohio, Oregon, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02565498's enrollment target sits among peer trials
210 1339th of 2000 higher than 656 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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