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ACTIVE NOT RECRUITING Phase 3

Preoperative vs Postoperative IMRT for Extremity/Truncal STS

NCT02565498 · View on ClinicalTrials.gov ↗

Study Summary

This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results in similar short-term wound healing complications as surgery followed by postoperative IGRT in patients with extremity or truncal soft tissue sarcoma. Half of the patients will receive preoperative radiotherapy, half will receive postoperative radiotherapy.

Conditions Studied

Interventions

  • RADIATION Preoperative intensity modulated radiation therapy
  • RADIATION Postoperative intensity modulated radiation therapy

Study Locations (8)

Ontario

  • The Ottawa Hospital Cancer Centre — Ottawa
  • Mount Sinai Hospital — Toronto
  • Princess Margaret Cancer Centre — Toronto

Massachusetts

  • Dana Farber Cancer Institute — Boston

Ohio

  • Cleveland Clinic Taussig Cancer Institute — Cleveland

Oregon

  • Oregon Health & Science University — Portland

Other

  • Cliniques Universitaires Saint-Luc — Brussels

Quebec

  • Hopital Maisonneuve-Rosemont — Montreal

Trial Details

FieldValue
Enrollment Target 210 participants
Start Date 2016-06
Est. Completion 2029-05
Phase Phase 3

Sponsor

Mount Sinai Hospital, Canada

33 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02565498

The ClinicalTrials.gov registry entry for NCT02565498 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 210 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mount Sinai Hospital, Canada, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Adult Soft Tissue Sarcoma appearing as the primary indexed condition, and to 2 interventions — of which Preoperative intensity modulated radiation therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02565498 reports 8 study locations spanning 6 distinct geographic areas — top geographies include Ontario, Massachusetts, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02565498 about?

NCT02565498 is a clinical study titled "Preoperative vs Postoperative IMRT for Extremity/Truncal STS". This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results in similar short-term wound healing complications as surgery followed by postoperative IGRT in patients with extremity or...

What is the current status of trial NCT02565498?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 210 participants. The study started on 2016-06. Estimated completion is 2029-05.

What conditions does trial NCT02565498 study?

This clinical trial studies the following conditions: Adult Soft Tissue Sarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02565498?

The interventions under investigation include: Preoperative intensity modulated radiation therapy (RADIATION), Postoperative intensity modulated radiation therapy (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02565498?

This trial is sponsored by Mount Sinai Hospital, Canada, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02565498 being conducted?

This trial has 8 study locations across Massachusetts, Ohio, Oregon, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial