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NCT02552225 · ClinicalTrials.gov registry record · Phase 2

Treatment of Chronic Laryngitis With Amitriptyline

A Phase 2 study, sponsored by Boston Medical Center.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT02552225: Clinical Trial Phase 2 study, sponsored by Boston Medical Center.

NCT02552225 is a Phase 2 study that was terminated before completion, run by Boston Medical Center. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02552225, a Phase 2 study, was terminated before completion, sponsored by Boston Medical Center.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

This randomized, double-blind, placebo-controlled trial will compare the effectiveness of amitriptyline versus placebo (inactive medication) in treating chronic laryngitis.

Primary Outcome

The Reflux Symptom Index (RSI) is a validated questionnaire consisting of 9 statements to be ranked on a scale of 0-5 (0=no problem, 5=severe problem). RSI scores can range from 0 to 45, with higher scores correlated with more reflux symptoms.

Interventions

  • OTHER Placebo
  • DRUG Amitriptyline

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2016-04
Est. Completion 2021-01-15
Phase Phase 2
Boston Medical Center

253 total trials

Why NCT02552225 stopped before completion

NCT02552225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02552225 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02552225 about?

NCT02552225 is a clinical study titled "Treatment of Chronic Laryngitis With Amitriptyline". This randomized, double-blind, placebo-controlled trial will compare the effectiveness of amitriptyline versus placebo (inactive medication) in treating chronic laryngitis.

What is the current status of trial NCT02552225?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2016-04. Estimated completion is 2021-01-15.

What interventions are being tested in trial NCT02552225?

The interventions under investigation include: Placebo (OTHER), Amitriptyline (DRUG).

Who is sponsoring clinical trial NCT02552225?

This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02552225's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02552225, the US trial registry maintained by the National Library of Medicine. NCT02552225 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.