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NCT02530814 · ClinicalTrials.gov registry record
Organochlorine Pesticide Exposure in Residents Near Lake Apopka
A clinical trial of Pesticide Exposure, sponsored by University of Florida.
- Completed
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT02530814: Completed study of Pesticide Exposure, sponsored by University of Florida.
NCT02530814 is a study of Pesticide Exposure that has completed, run by University of Florida. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02530814, a study of Pesticide Exposure, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
In the Lake Apopka, Florida area for over 50 years starting in the 1940s, organochlorine pesticides (OCPs) including 4,4'-dichlorodiphenyltrichloroethane (DDT), dieldrin, chlordane, toxaphene and more recently methoxychlor were sprayed on farmlands in order to control pests and to improve crop harvests. For most of those years, the farmworkers were exposed to the pesticides as part of their work. Because of their lipophilic (fat soluble) nature, these organochlorine pesticides (OCPs) are readily taken up into the body and not readily eliminated. Therefore, they can be detected in exposed individuals for many years after the exposure. There is some evidence that certain OCPs can cause or exacerbate medical problems in sensitive individuals. For example, exposure to some OCPs has been associated with development of Parkinsonism. Exposure to other OCPs has been associated with development of lupus erythematosus, an auto-immune disease. Other adverse effects of exposure to OCPs are endocrine disruption because some OCPs mimic estrogens and others mimic androgens, or may have mixed interactions with steroid receptors. In this research study the investigators aim is to test the blood from former farmworkers during the 1940s through the late 1970s who reside in the Lake Apopka area for OCPs and for the auto-antibodies. In addition, questionnaires will provide insight on their health status and health concerns.
Primary Outcome
Blood collected will be analyzed for DDT, dieldrin, chlordane, methoxychlor and the metabolites of DDT and methoxychlor. The data will be compared between the groups.
Conditions Studied
Interventions
- OTHER Blood Collection
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2015-11 |
| Est. Completion | 2016-03 |
What the finished NCT02530814 record still lists
NCT02530814 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 1 condition, with Pesticide Exposure appearing as the primary indexed condition, and to 1 intervention - of which Blood Collection is the first listed.
NCT02530814 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT02530814 about?
NCT02530814 is a clinical study titled "Organochlorine Pesticide Exposure in Residents Near Lake Apopka". In the Lake Apopka, Florida area for over 50 years starting in the 1940s, organochlorine pesticides (OCPs) including 4,4'-dichlorodiphenyltrichloroethane (DDT), dieldrin, chlordane, toxaphene and more recently methoxychlor were sprayed on farmlands in order to control pests and to improve crop harve...
What is the current status of trial NCT02530814?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2015-11. Estimated completion is 2016-03.
What conditions does trial NCT02530814 study?
This clinical trial studies the following conditions: Pesticide Exposure.
What interventions are being tested in trial NCT02530814?
The interventions under investigation include: Blood Collection (OTHER).
Who is sponsoring clinical trial NCT02530814?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02530814 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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