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NCT02523690 · ClinicalTrials.gov registry record · Phase 1

Evaluating Muscle Weakness Improvement With Lorcaserin in ICU

A Phase 1 study, sponsored by Johns Hopkins University.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT02523690: Clinical Trial Phase 1 study, sponsored by Johns Hopkins University.

NCT02523690 is a Phase 1 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02523690, a Phase 1 study, was terminated before completion, sponsored by Johns Hopkins University.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

ICU acquired muscle weakness is a significant problem in patients recovering from critical illness. This trial will evaluate the safety and efficacy of a drug in improving muscle weakness in critically ill patients.

Primary Outcome

Hand grip strength measured using a dynamometer (measured in kilograms, then compared to age- and sex-matched population norms to yield percent predicted strength - higher is better)

Interventions

  • DRUG Placebo
  • DRUG Lorcaserin

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2015-12
Est. Completion 2017-12
Phase Phase 1
Johns Hopkins University

1,448 total trials

Why NCT02523690 stopped before completion

NCT02523690 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02523690 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02523690 about?

NCT02523690 is a clinical study titled "Evaluating Muscle Weakness Improvement With Lorcaserin in ICU". ICU acquired muscle weakness is a significant problem in patients recovering from critical illness. This trial will evaluate the safety and efficacy of a drug in improving muscle weakness in critically ill patients.

What is the current status of trial NCT02523690?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2015-12. Estimated completion is 2017-12.

What interventions are being tested in trial NCT02523690?

The interventions under investigation include: Placebo (DRUG), Lorcaserin (DRUG).

Who is sponsoring clinical trial NCT02523690?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02523690's enrollment target sits among peer trials

5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02523690, the US trial registry maintained by the National Library of Medicine. NCT02523690 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.