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NCT02502006 · ClinicalTrials.gov registry record · Phase 1
Variability in Response to Non-steroidal Anti-inflammatory Drugs
A Phase 1 study, sponsored by University of Pennsylvania.
- Terminated
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT02502006: Clinical Trial Phase 1 study, sponsored by University of Pennsylvania.
NCT02502006 is a Phase 1 study that was terminated before completion, run by University of Pennsylvania. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02502006, a Phase 1 study, was terminated before completion, sponsored by University of Pennsylvania.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This research study will evaluate inter-individual variability in the response to the non-steroidal anti-inflammatory drugs (NSAIDs), celecoxib and naproxen, among healthy adults. It will also investigate what factors, like age, sex, or genetic background, cause this variability.
Primary Outcome
COX-1 activity was measured ex vivo using a whole blood assay. Thromboxane A2 serum concentrations were quantified before, and 0.5, 1, 2, 4, 8, and 12 h after treatment and expressed as AUC over the 12 hour dosing interval.
Interventions
- DRUG Placebo
- DRUG Celecoxib
- DRUG Naproxen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2015-11 |
| Est. Completion | 2022-09 |
| Phase | Phase 1 |
Why NCT02502006 stopped before completion
NCT02502006 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02502006 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02502006 about?
NCT02502006 is a clinical study titled "Variability in Response to Non-steroidal Anti-inflammatory Drugs". This research study will evaluate inter-individual variability in the response to the non-steroidal anti-inflammatory drugs (NSAIDs), celecoxib and naproxen, among healthy adults. It will also investigate what factors, like age, sex, or genetic background, cause this variability.
What is the current status of trial NCT02502006?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2015-11. Estimated completion is 2022-09.
What interventions are being tested in trial NCT02502006?
The interventions under investigation include: Placebo (DRUG), Celecoxib (DRUG), Naproxen (DRUG).
Who is sponsoring clinical trial NCT02502006?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02502006's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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