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NCT02496065 · ClinicalTrials.gov registry record · Phase 1

Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery

A Phase 1 study, sponsored by Blaze Bioscience.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT02496065: Completed Phase 1 study, sponsored by Blaze Bioscience.

NCT02496065 is a Phase 1 study that has completed, run by Blaze Bioscience. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02496065, a Phase 1 study, has completed, sponsored by Blaze Bioscience.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

Surgery is the primary treatment modality for many types of cancer and the extent of surgical resection is directly related to patient survival. However, it is often difficult for surgeons to distinguish normal from neoplastic tissue or to detect metastatic disease or tumor-infiltrated lymph nodes. In some sites, surgical precision is also required to avoid damage to critical normal tissues. The purpose of this exploratory study is to evaluate the intra-operative and ex vivo fluorescence of BLZ-100 in tumor samples from subjects with breast cancer.

Primary Outcome

Safety will be assessed by physical examination and measurement of vital signs and laboratory safety parameters. These assessments will be used to determine whether a subject experienced an AE.

Interventions

  • DRUG BLZ-100

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2015-07
Est. Completion 2017-01
Phase Phase 1
Blaze Bioscience

4 total trials

What the finished NCT02496065 record still lists

NCT02496065 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 1 intervention - of which BLZ-100 is the first listed.

NCT02496065 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02496065 about?

NCT02496065 is a clinical study titled "Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery". Surgery is the primary treatment modality for many types of cancer and the extent of surgical resection is directly related to patient survival. However, it is often difficult for surgeons to distinguish normal from neoplastic tissue or to detect metastatic disease or tumor-infiltrated lymph nodes. ...

What is the current status of trial NCT02496065?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2015-07. Estimated completion is 2017-01.

What interventions are being tested in trial NCT02496065?

The interventions under investigation include: BLZ-100 (DRUG).

Who is sponsoring clinical trial NCT02496065?

This trial is sponsored by Blaze Bioscience, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02496065's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02496065, the US trial registry maintained by the National Library of Medicine. NCT02496065 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.