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NCT02467361 · ClinicalTrials.gov registry record · Phase 1

A Study of BBI608 Administered in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Cancers

A Phase 1 study, sponsored by Sumitomo Pharma America.

Completed
Registry status
Phase 1
Development phase
104
Enrollment target

NCT02467361: Completed Phase 1 study, sponsored by Sumitomo Pharma America.

NCT02467361 is a Phase 1 study that has completed, run by Sumitomo Pharma America. The registered enrollment target is 104 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02467361, a Phase 1 study, has completed, sponsored by Sumitomo Pharma America.

COMPLETED
Registry status
Phase 1
Development phase
104 participants
Enrollment target

Study Summary

This is an open label, multi-center, Phase 1/2 study of BBI608 administered in combination with immunotherapy in adult patients with advanced cancers. The goal of the study is to determine the RP2D of BBI608 in combination with each of the immunotherapeutic agents.

Interventions

  • DRUG Pembrolizumab
  • DRUG Nivolumab
  • DRUG Ipilimumab
  • DRUG BBI608

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2015-08
Est. Completion 2021-01-29
Phase Phase 1
Sumitomo Pharma America

168 total trials

What the finished NCT02467361 record still lists

NCT02467361 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% higher).

The record links to 0 conditions, and to 4 interventions - of which Pembrolizumab is the first listed.

NCT02467361 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02467361 about?

NCT02467361 is a clinical study titled "A Study of BBI608 Administered in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Cancers". This is an open label, multi-center, Phase 1/2 study of BBI608 administered in combination with immunotherapy in adult patients with advanced cancers. The goal of the study is to determine the RP2D of BBI608 in combination with each of the immunotherapeutic agents.

What is the current status of trial NCT02467361?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 104 participants. The study started on 2015-08. Estimated completion is 2021-01-29.

What interventions are being tested in trial NCT02467361?

The interventions under investigation include: Pembrolizumab (DRUG), Nivolumab (DRUG), Ipilimumab (DRUG), BBI608 (DRUG).

Who is sponsoring clinical trial NCT02467361?

This trial is sponsored by Sumitomo Pharma America, which has 168 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02467361's enrollment target sits among peer trials

104 536th of 2000 higher than 1,460 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02467361, the US trial registry maintained by the National Library of Medicine. NCT02467361 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.