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NCT02460354 · ClinicalTrials.gov registry record · Phase 1
Metformin and Congenital Nephrogenic Diabetes Insipidus
A Phase 1 study, sponsored by Emory University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 2
- Enrollment target
NCT02460354: Clinical Trial Phase 1 study, sponsored by Emory University.
NCT02460354 is a Phase 1 study that was terminated before completion, run by Emory University. The registered enrollment target is 2 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02460354, a Phase 1 study, was terminated before completion, sponsored by Emory University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether metformin can increase urine concentration (osmolality) and decrease the amount of urine in patients with congenital nephrogenic diabetes insipidus (NDI).
Primary Outcome
Urine osmolality is a measure of urine concentration. Urine osmolality will be measured using a Wescor vapor pressure osmometer. A normal range for urine osmolality is approximately 500-850 mOsm/kg water. Change is the difference in average osmolality from baseline to 7 hours.
Interventions
- DRUG Metformin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2015-09 |
| Est. Completion | 2017-06 |
| Phase | Phase 1 |
Why NCT02460354 stopped before completion
NCT02460354 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Metformin is the first listed.
NCT02460354 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02460354 about?
NCT02460354 is a clinical study titled "Metformin and Congenital Nephrogenic Diabetes Insipidus". The purpose of this study is to determine whether metformin can increase urine concentration (osmolality) and decrease the amount of urine in patients with congenital nephrogenic diabetes insipidus (NDI).
What is the current status of trial NCT02460354?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2015-09. Estimated completion is 2017-06.
What interventions are being tested in trial NCT02460354?
The interventions under investigation include: Metformin (DRUG).
Who is sponsoring clinical trial NCT02460354?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02460354's enrollment target sits among peer trials
2 2000th of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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