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NCT02459210 · ClinicalTrials.gov registry record · NA
Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis
A NA study, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 58
- Enrollment target
NCT02459210 is a NA study that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 58 participants.
The verdict
NCT02459210, a NA study, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 58 participants
- Enrollment target
Study Summary
The purpose of this study is to test the feasibility of a modification of CET (Cognitive Enhancement Therapy) to address symptomatic and functional difficulties associated with Clinical High Risk for Psychosis (CHR). Cognition for Learning and for Understanding Everyday Social Situations (CLUES) is designed to improve cognitive functioning (e.g., memory, attention, planning, etc.) in order to improve school, work, and social functioning. CLUES includes the following: 1. Computerized cognitive remediation ("exercises") to improve cognition. 2. Social-cognitive skills group designed to teach participants to act wisely in social situations. 3. Individual coaching sessions designed to enhance translation of skills learned from computer exercises and the group into real life. CLUES is based on Hogarty and Greenwald's Cognitive Enhancement Therapy (CET), which was designed for treating individuals with schizophrenia. Research on CET for individuals with schizophrenia has found that CET appears to have helped participants improve cognition and social and work functioning. This study will investigate the feasibility of CLUES for young people who are showing signs of clinical risk for psychosis. Part 1: Preliminary open label trial of CLUES (n=8) to examine preliminary evidence of target engagement (change in cognition and social cognition), to refine assessment and recruitment approaches, to further optimize the treatment manual, and to ascertain feasibility and tolerability. Part 2: Preliminary randomized controlled trial of CLUES vs supportive therapy (ST) + computer games to explore preliminary evidence of efficacy of CLUES vs. the control treatment (n=30).
Interventions
- BEHAVIORAL CLUES
- BEHAVIORAL therapy and computer games
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2015-01 |
| Est. Completion | 2019-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02459210
The ClinicalTrials.gov registry entry for NCT02459210 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which CLUES is the first listed.
NCT02459210 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02459210 about?
NCT02459210 is a clinical study titled "Adaptation of Cognitive Enhancement Therapy for Persons at Clinical High Risk for Psychosis". The purpose of this study is to test the feasibility of a modification of CET (Cognitive Enhancement Therapy) to address symptomatic and functional difficulties associated with Clinical High Risk for Psychosis (CHR). Cognition for Learning and for Understanding Everyday Social Situations (CLUES) is...
What is the current status of trial NCT02459210?
This trial is currently completed. It is a NA study. The enrollment target is 58 participants. The study started on 2015-01. Estimated completion is 2019-01.
What interventions are being tested in trial NCT02459210?
The interventions under investigation include: CLUES (BEHAVIORAL), therapy and computer games (BEHAVIORAL).
Who is sponsoring clinical trial NCT02459210?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
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