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NCT02457806 · ClinicalTrials.gov registry record · Phase 1
Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers
A Phase 1 study, sponsored by St. Renatus.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT02457806: Completed Phase 1 study, sponsored by St. Renatus.
NCT02457806 is a Phase 1 study that has completed, run by St. Renatus. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02457806, a Phase 1 study, has completed, sponsored by St. Renatus.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
To compare the efficacy of Kovacaine Mist administered bilaterally to that of Kovacaine Mist administered unilaterally with respect to global profound pulpal anesthesia in target teeth numbers 4-13.
Primary Outcome
Achievement of Global Profound Pulpal Anesthesia (GPPA) as having all three target maxillary teeth \[nos. 4(or 5), 6, and 8 for the right side or nos. 9, 11, and 13 (or 12) for the left-side\] reach an EPT of 80 within 20 minutes of the final spray of study drug
Interventions
- DRUG Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
- DRUG Placebo spray
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2011-08 |
| Est. Completion | 2011-10 |
| Phase | Phase 1 |
What the finished NCT02457806 record still lists
NCT02457806 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which Tetracaine HCl 3% and Oxymetazoline HCl 0.05% is the first listed.
NCT02457806 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02457806 about?
NCT02457806 is a clinical study titled "Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers". To compare the efficacy of Kovacaine Mist administered bilaterally to that of Kovacaine Mist administered unilaterally with respect to global profound pulpal anesthesia in target teeth numbers 4-13.
What is the current status of trial NCT02457806?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2011-08. Estimated completion is 2011-10.
What interventions are being tested in trial NCT02457806?
The interventions under investigation include: Tetracaine HCl 3% and Oxymetazoline HCl 0.05% (DRUG), Placebo spray (DRUG).
Who is sponsoring clinical trial NCT02457806?
This trial is sponsored by St. Renatus, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02457806's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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