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NCT02455414 · ClinicalTrials.gov registry record
Tracking Neurodegeneration in Early Wolfram Syndrome
A clinical trial, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- 101
- Enrollment target
NCT02455414 is a clinical trial that has completed, run by Washington University School of Medicine. The registered enrollment target is 101 participants.
The verdict
NCT02455414 has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- 101 participants
- Enrollment target
Study Summary
The goal of this study is to determine the pattern of early neurodegenerative changes in WFS (Wolfram Syndrome). The investigator will perform cross-sectional and longitudinal assessments of youth with WFS, targeting sensitive neural systems with quantified neuroimaging and behavioral measures. In addition, the investigator will establish the utility of a WFS severity rating scale (WFS Unified Rating Scale or WURS). Preliminary data support the feasibility of this approach and its potential to generate important new information about neurodevelopmental and neurodegenerative patterns in WFS. This work is necessary to position the field for future clinical trials to test interventions for WFS neurodegeneration. Ultimately, a better understanding of the trajectory of neurodegeneration in WFS and the development of effective interventions may be relevant to other more common neurodegenerative and endocrine (Type 1 and Type 2 diabetes) diseases in which ER stress has been implicated.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2012-04 |
| Est. Completion | 2017-07-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02455414
The ClinicalTrials.gov registry entry for NCT02455414 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 101 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT02455414 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02455414 about?
NCT02455414 is a clinical study titled "Tracking Neurodegeneration in Early Wolfram Syndrome". The goal of this study is to determine the pattern of early neurodegenerative changes in WFS (Wolfram Syndrome). The investigator will perform cross-sectional and longitudinal assessments of youth with WFS, targeting sensitive neural systems with quantified neuroimaging and behavioral measures. In a...
What is the current status of trial NCT02455414?
This trial is currently completed. The enrollment target is 101 participants. The study started on 2012-04. Estimated completion is 2017-07-12.
Who is sponsoring clinical trial NCT02455414?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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