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NCT02448043 · ClinicalTrials.gov registry record · NA

Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure

A NA study of Intraocular Pressure and Nail Growth Cessation, sponsored by Northwestern University.

Completed
Registry status
NA
Development phase
45
Enrollment target
1
Study location

NCT02448043: Completed NA study of Intraocular Pressure and Nail Growth Cessation, sponsored by Northwestern University.

NCT02448043 is a NA study of Intraocular Pressure and Nail Growth Cessation that has completed, run by Northwestern University. The registered enrollment target is 45 participants, below the 83-participant average among 9 other Intraocular Pressure trials with a reported enrollment target (46% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02448043, a NA study of Intraocular Pressure and Nail Growth Cessation, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
NA
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

Topical prostaglandin agents are used to help reduce eye pressure in glaucoma patients. Bimatoprost (Lumigan 0.01%) is such an agent (Allergan, Inc.). Several of our patients on bimatoprost and an observational study of patients on bimatoprost in another center reported that fingernails grew longer and became less brittle using the topical eye drops to the eyes. The purpose of the double-blinded study is to determine whether the application of the eye drops directly to the proximal nail fold of one hand using the opposite hand as a control will result in longer nails, less brittle nails, and reduced eye pressures should any of the medication be absorbed into the systemic circulation.

Primary Outcome

Measured by digital calipers (Ironton 6 in. Stainless Steel Digital Fractional Caliper, Northern Tool and Equipment, Burnsville, MN, USA)

Interventions

  • DRUG Bimatoprost 0.01%
  • OTHER Placebo: saline

Study Locations (1)

Illinois

  • David J. Palmer, MD - Glenview

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2015-06-04
Est. Completion 2016-05-06
Phase NA
Northwestern University

1,209 total trials

What the finished NCT02448043 record still lists

NCT02448043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 83-participant average among 9 other Intraocular Pressure trials with a reported enrollment target (46% lower).

The record links to 2 conditions, with Intraocular Pressure appearing as the primary indexed condition, and to 2 interventions - of which Bimatoprost 0.01% is the first listed.

NCT02448043 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT02448043 about?

NCT02448043 is a clinical study titled "Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure". Topical prostaglandin agents are used to help reduce eye pressure in glaucoma patients. Bimatoprost (Lumigan 0.01%) is such an agent (Allergan, Inc.). Several of our patients on bimatoprost and an observational study of patients on bimatoprost in another center reported that fingernails grew longer ...

What is the current status of trial NCT02448043?

This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2015-06-04. Estimated completion is 2016-05-06.

What conditions does trial NCT02448043 study?

This clinical trial studies the following conditions: Intraocular Pressure, Nail Growth Cessation.

What interventions are being tested in trial NCT02448043?

The interventions under investigation include: Bimatoprost 0.01% (DRUG), Placebo: saline (OTHER).

Who is sponsoring clinical trial NCT02448043?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02448043 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Intraocular Pressure

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02448043's enrollment target sits among peer trials

45 6th of 9 higher than 4 of 9 other Intraocular Pressure trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Intraocular Pressure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02448043, the US trial registry maintained by the National Library of Medicine. NCT02448043 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.