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NCT02447224 · ClinicalTrials.gov registry record · Early Phase 1
Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis
A Early Phase 1 study, sponsored by Olive View-UCLA Education & Research Institute.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 30
- Enrollment target
NCT02447224: Completed Early Phase 1 study, sponsored by Olive View-UCLA Education & Research Institute.
NCT02447224 is a Early Phase 1 study that has completed, run by Olive View-UCLA Education & Research Institute. The registered enrollment target is 30 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02447224, a Early Phase 1 study, has completed, sponsored by Olive View-UCLA Education & Research Institute.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
The major goal of the project is to demonstrate the feasibility of conducting a multi-center randomized clinical trial of antibiotic therapy versus appendectomy for the treatment of patients with acute uncomplicated appendicitis by conducting a single-site pilot study so as to optimize the chance of a large multi-center clinical trial's future success.
Primary Outcome
The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) criteria and definitions for major complications will be used. In addition, antibiotic related complications will be evaluated, i.e., antibiotic-related/Clostridium difficile colitis and antibiotic reaction requiring hospitalization.
Interventions
- PROCEDURE Appendectomy
- DRUG 1 gm IV ertapenem at enrollment
- DRUG 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2015-03 |
| Est. Completion | 2017-12-31 |
| Phase | Early Phase 1 |
What the finished NCT02447224 record still lists
NCT02447224 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 3 interventions - of which Appendectomy is the first listed.
NCT02447224 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02447224 about?
NCT02447224 is a clinical study titled "Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis". The major goal of the project is to demonstrate the feasibility of conducting a multi-center randomized clinical trial of antibiotic therapy versus appendectomy for the treatment of patients with acute uncomplicated appendicitis by conducting a single-site pilot study so as to optimize the chance of...
What is the current status of trial NCT02447224?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2015-03. Estimated completion is 2017-12-31.
What interventions are being tested in trial NCT02447224?
The interventions under investigation include: Appendectomy (PROCEDURE), 1 gm IV ertapenem at enrollment (DRUG), 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days (DRUG).
Who is sponsoring clinical trial NCT02447224?
This trial is sponsored by Olive View-UCLA Education & Research Institute, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02447224's enrollment target sits among peer trials
30 807th of 2000 higher than 1,075 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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