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NCT02445807 · ClinicalTrials.gov registry record · Phase 3

A Study of the Efficacy and Safety of DFD-06 Cream in the Treatment of Moderate to Severe Plaque Psoriasis

A Phase 3 study, sponsored by Promius Pharma.

Completed
Registry status
Phase 3
Development phase
265
Enrollment target

NCT02445807: Completed Phase 3 study, sponsored by Promius Pharma.

NCT02445807 is a Phase 3 study that has completed, run by Promius Pharma. The registered enrollment target is 265 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02445807, a Phase 3 study, has completed, sponsored by Promius Pharma.

COMPLETED
Registry status
Phase 3
Development phase
265 participants
Enrollment target

Study Summary

This study will compare the efficacy and safety of DFD-06 Cream to Vehicle Cream for topical treatment of moderate to severe plaque psoriasis after 3, 7, and 14 days of treatment.

Primary Outcome

The primary efficacy endpoint is the percentage of subjects with treatment success (defined as IGA = 0 or 1 and at least a 2 grade reduction from Baseline) at the Day 15 visit. The primary analysis was done with multiple imputations. Results are combined analyses from 5 imputed data sets.

Interventions

  • DRUG Vehicle Cream
  • DRUG DFD06-Cream

Trial Details

FieldValue
Enrollment Target 265 participants
Start Date 2015-12
Est. Completion 2016-07
Phase Phase 3
Promius Pharma

9 total trials

What the finished NCT02445807 record still lists

NCT02445807 is an interventional study that assigns participants to a tested intervention. The registered 265 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (66% lower).

The record links to 0 conditions, and to 2 interventions - of which Vehicle Cream is the first listed.

NCT02445807 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02445807 about?

NCT02445807 is a clinical study titled "A Study of the Efficacy and Safety of DFD-06 Cream in the Treatment of Moderate to Severe Plaque Psoriasis". This study will compare the efficacy and safety of DFD-06 Cream to Vehicle Cream for topical treatment of moderate to severe plaque psoriasis after 3, 7, and 14 days of treatment.

What is the current status of trial NCT02445807?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 265 participants. The study started on 2015-12. Estimated completion is 2016-07.

What interventions are being tested in trial NCT02445807?

The interventions under investigation include: Vehicle Cream (DRUG), DFD06-Cream (DRUG).

Who is sponsoring clinical trial NCT02445807?

This trial is sponsored by Promius Pharma, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02445807's enrollment target sits among peer trials

265 1223rd of 2000 higher than 776 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02445807, the US trial registry maintained by the National Library of Medicine. NCT02445807 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.