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NCT02444208 · ClinicalTrials.gov registry record · NA
A Feasibility Trial for Inhibitory-Control Training to Reduce Cocaine Use
A NA study, sponsored by University of Kentucky.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT02444208 is a NA study that has completed, run by University of Kentucky. The registered enrollment target is 40 participants.
The verdict
NCT02444208, a NA study, has completed, sponsored by University of Kentucky.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Cocaine abuse is an unrelenting public-health concern. Behavioral therapies are considered the "standard of care" for reducing cocaine use and preventing relapse. However, even with intense behavioral interventions, rates of relapse to cocaine use are discouragingly high (i.e., 60-95% of patients return to drug use). Novel strategies are urgently needed to improve treatment outcomes for cocaine-use disorders. The overarching goal of this project is to assess the feasibility, acceptability and initial efficacy of an innovative cocaine-based inhibitory-control training procedure. This goal will be accomplished through the conduct of a Stage I pilot trial. Cocaine-dependent participants will be enrolled and randomized to receive inhibitory-control training to cocaine or neutral images (N=20/condition). This proposed intervention, cocaine based inhibitory-control training, will be delivered using an innovative computer program which teaches cocaine abusers to inhibit a pre-potent response to cocaine or neutral cues. The primary hypothesis is the proposed procedures are feasible and acceptable to the participants. Feasibility will be assessed by determining time needed to enroll the target sample; adaptive randomization outcomes; participant attendance, completion and adherence to study procedures. Acceptability will be determined using a Treatment Acceptability Questionnaire. The secondary hypothesis is that participants receiving cocaine-based inhibitory-control training will reduce their drug use to a greater extent than their counterparts in the neutral-image condition. Reduced cocaine use will be demonstrated by fewer positive-urine samples using qualitative urinalysis and a reduction in levels of benzoylecgonine as determined by quantitative urinalysis (i.e., ELISA). The third hypothesis is that participants receiving cocaine-based inhibitory-control training will show improved inhibitory control and neurocognitive functioning relative to their counterparts in the
Interventions
- BEHAVIORAL Active Inhibitory Control Training
- BEHAVIORAL Neutral Inhibitory Control Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2015-05 |
| Est. Completion | 2018-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02444208
The ClinicalTrials.gov registry entry for NCT02444208 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Kentucky, which has 54 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Active Inhibitory Control Training is the first listed.
NCT02444208 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02444208 about?
NCT02444208 is a clinical study titled "A Feasibility Trial for Inhibitory-Control Training to Reduce Cocaine Use". Cocaine abuse is an unrelenting public-health concern. Behavioral therapies are considered the "standard of care" for reducing cocaine use and preventing relapse. However, even with intense behavioral interventions, rates of relapse to cocaine use are discouragingly high (i.e., 60-95% of patients re...
What is the current status of trial NCT02444208?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2015-05. Estimated completion is 2018-06.
What interventions are being tested in trial NCT02444208?
The interventions under investigation include: Active Inhibitory Control Training (BEHAVIORAL), Neutral Inhibitory Control Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT02444208?
This trial is sponsored by University of Kentucky, which has 54 total clinical trials registered on ClinicalTrials.gov.
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