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NCT02436460 · ClinicalTrials.gov registry record · Phase 1
A Study of AbGn-168H in Patients With Steroid Refractory Acute Graft-vs-Host Disease After Donor Stem Cell Transplant
A Phase 1 study, sponsored by AbGenomics B.V Taiwan Branch.
- Terminated
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT02436460: Clinical Trial Phase 1 study, sponsored by AbGenomics B.V Taiwan Branch.
NCT02436460 is a Phase 1 study that was terminated before completion, run by AbGenomics B.V Taiwan Branch. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02436460, a Phase 1 study, was terminated before completion, sponsored by AbGenomics B.V Taiwan Branch.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
This study is to establish the safety, determine if there is an improvement in steroid refractory acute graft-vs-host disease (aGvHD) compared to historical cohorts, and determine the changes of aGvHD-associated T-cell clones in patients with steroid-refractory aGVHD following allogeneic hematopoietic cell transplantation administered AbGn-168H once weekly for 4 weeks.
Primary Outcome
Grade 3 to 5 adverse events considered at least possibly-related to neihulizumab
Interventions
- BIOLOGICAL AbGn-168H
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2015-05 |
| Est. Completion | 2016-03 |
| Phase | Phase 1 |
Why NCT02436460 stopped before completion
NCT02436460 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which AbGn-168H is the first listed.
NCT02436460 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02436460 about?
NCT02436460 is a clinical study titled "A Study of AbGn-168H in Patients With Steroid Refractory Acute Graft-vs-Host Disease After Donor Stem Cell Transplant". This study is to establish the safety, determine if there is an improvement in steroid refractory acute graft-vs-host disease (aGvHD) compared to historical cohorts, and determine the changes of aGvHD-associated T-cell clones in patients with steroid-refractory aGVHD following allogeneic hematopoiet...
What is the current status of trial NCT02436460?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2015-05. Estimated completion is 2016-03.
What interventions are being tested in trial NCT02436460?
The interventions under investigation include: AbGn-168H (BIOLOGICAL).
Who is sponsoring clinical trial NCT02436460?
This trial is sponsored by AbGenomics B.V Taiwan Branch, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02436460's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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