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NCT02434627 · ClinicalTrials.gov registry record · Phase 1
Sodium Nitrate for Muscular Dystrophy
A Phase 1 study, sponsored by Cedars-Sinai Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT02434627: Completed Phase 1 study, sponsored by Cedars-Sinai Medical Center.
NCT02434627 is a Phase 1 study that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02434627, a Phase 1 study, has completed, sponsored by Cedars-Sinai Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The investigators' previous work in males with Becker Muscular Dystrophy shows that functional sympatholysis is restored by acute inorganic nitrate supplementation. This was translated from work using the mdx mouse model of dystrophinopathy. Recent work has shown that there is a frank improvement in grip strength when mdx mice are treated with an inorganic Nitric Oxide (NO) donor. The purpose of this study is to determine if chronic treatment with an inorganic NO donor can benefit patients with muscular dystrophy beyond blood flow regulation.
Interventions
- DRUG Sodium Nitrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2015-06 |
| Est. Completion | 2018-04 |
| Phase | Phase 1 |
What the finished NCT02434627 record still lists
NCT02434627 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Sodium Nitrate is the first listed.
NCT02434627 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02434627 about?
NCT02434627 is a clinical study titled "Sodium Nitrate for Muscular Dystrophy". The investigators' previous work in males with Becker Muscular Dystrophy shows that functional sympatholysis is restored by acute inorganic nitrate supplementation. This was translated from work using the mdx mouse model of dystrophinopathy. Recent work has shown that there is a frank improvement in...
What is the current status of trial NCT02434627?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2015-06. Estimated completion is 2018-04.
What interventions are being tested in trial NCT02434627?
The interventions under investigation include: Sodium Nitrate (DRUG).
Who is sponsoring clinical trial NCT02434627?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02434627's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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