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NCT02425449 · ClinicalTrials.gov registry record · Phase 4
Fade Upon TOF Stimulation Induced by Succinylcholine
A Phase 4 study, sponsored by University of Toledo Health Science Campus.
- Completed
- Registry status
- Phase 4
- Development phase
- 19
- Enrollment target
NCT02425449 is a Phase 4 study that has completed, run by University of Toledo Health Science Campus. The registered enrollment target is 19 participants.
The verdict
NCT02425449, a Phase 4 study, has completed, sponsored by University of Toledo Health Science Campus.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 19 participants
- Enrollment target
Study Summary
Muscle relaxants are medications used during surgery to facilitate surgical access. The effect of the muscle relaxant medications is measured by stimulation a motor nerve and measuring the force of the resultant muscle contraction. Based on the mechanism of action, two kinds of muscle relaxants are described. First a nondepolarizing muscle relaxant and the second kind is the depolarizing muscle relaxant. These two kinds of muscle relaxants can be distinguished by rapidly stimulating the nerve 4 times over 2 seconds (Train of four or TOF). The nondepolarizing muscle relaxants produce fade ie successive muscle contractions are less forceful than the preceding ones. Whereas the depolarizing muscle relaxants are generally believed to produce four contractions of equal strength. However, there is some indication that this may not be entirely correct. There is evidence that depolarizing muscle relaxants also may produce fade. The investigators are conducting the following study to determine if indeed depolarizing muscle relaxants produce fade. The investigators would also like to characterize the fade ie differences during onset and offset of the block and the effect of the dose on the degree on the fade.
Interventions
- DRUG Succinylcholine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2015-04 |
| Est. Completion | 2017-01-04 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02425449
The ClinicalTrials.gov registry entry for NCT02425449 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Toledo Health Science Campus, which has 26 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Succinylcholine is the first listed.
NCT02425449 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02425449 about?
NCT02425449 is a clinical study titled "Fade Upon TOF Stimulation Induced by Succinylcholine". Muscle relaxants are medications used during surgery to facilitate surgical access. The effect of the muscle relaxant medications is measured by stimulation a motor nerve and measuring the force of the resultant muscle contraction. Based on the mechanism of action, two kinds of muscle relaxants are ...
What is the current status of trial NCT02425449?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 19 participants. The study started on 2015-04. Estimated completion is 2017-01-04.
What interventions are being tested in trial NCT02425449?
The interventions under investigation include: Succinylcholine (DRUG).
Who is sponsoring clinical trial NCT02425449?
This trial is sponsored by University of Toledo Health Science Campus, which has 26 total clinical trials registered on ClinicalTrials.gov.
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