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NCT02400476 · ClinicalTrials.gov registry record · Phase 2

An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide

A Phase 2 study, sponsored by Puma Biotechnology.

Completed
Registry status
Phase 2
Development phase
563
Enrollment target

NCT02400476 is a Phase 2 study that has completed, run by Puma Biotechnology. The registered enrollment target is 563 participants.

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The verdict

NCT02400476, a Phase 2 study, has completed, sponsored by Puma Biotechnology.

COMPLETED
Registry status
Phase 2
Development phase
563 participants
Enrollment target

Study Summary

An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early-Stage HER2+ Breast Cancer Treated with Neratinib and Loperamide or other prophylactic measures.

Interventions

  • DRUG Neratinib
  • DRUG Budesonide
  • DRUG Loperamide
  • DRUG Colestipol

Trial Details

FieldValue
Enrollment Target 563 participants
Start Date 2015-02
Est. Completion 2021-04-22
Phase Phase 2

Sponsor

Puma Biotechnology

28 total trials

What the Registry Record Tells You About NCT02400476

The ClinicalTrials.gov registry entry for NCT02400476 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 563 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Puma Biotechnology, which has 28 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Neratinib is the first listed.

NCT02400476 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02400476 about?

NCT02400476 is a clinical study titled "An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide". An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early-Stage HER2+ Breast Cancer Treated with Neratinib and Loperamide or other prophylactic measures.

What is the current status of trial NCT02400476?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 563 participants. The study started on 2015-02. Estimated completion is 2021-04-22.

What interventions are being tested in trial NCT02400476?

The interventions under investigation include: Neratinib (DRUG), Budesonide (DRUG), Loperamide (DRUG), Colestipol (DRUG).

Who is sponsoring clinical trial NCT02400476?

This trial is sponsored by Puma Biotechnology, which has 28 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.