Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02392351 · ClinicalTrials.gov registry record · NA

Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension (REDUCE HTN:REINFORCE)

A NA study, sponsored by Boston Scientific Corporation.

Completed
Registry status
NA
Development phase
51
Enrollment target

NCT02392351: Completed NA study, sponsored by Boston Scientific Corporation.

NCT02392351 is a NA study that has completed, run by Boston Scientific Corporation. The registered enrollment target is 51 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02392351, a NA study, has completed, sponsored by Boston Scientific Corporation.

COMPLETED
Registry status
NA
Development phase
51 participants
Enrollment target

Study Summary

The REDUCE HTN: REINFORCE study is being conducted to determine whether the Vessix Reduce™ Catheter and Vessix™ Generator for the treatment of uncontrolled hypertension (off-treatment office systolic blood pressure ≥150 mmHg and ≤180 mmHg) shows acceptable performance at 8 weeks when compared to a masked procedure (renal angiogram).

Primary Outcome

Change (mean reduction) in average 24-hour Ambulatory Systolic Blood Pressure (ASBP) through 8 weeks post randomization in subjects treated with renal denervation (Test) and subjects treated with masked procedure (Control)

Interventions

  • DEVICE Renal Denervation (Vessix)
  • DEVICE Renal Angiography

Trial Details

FieldValue
Enrollment Target 51 participants
Start Date 2015-04
Est. Completion 2019-08-02
Phase NA
Boston Scientific Corporation

280 total trials

What the finished NCT02392351 record still lists

NCT02392351 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Renal Denervation (Vessix) is the first listed.

NCT02392351 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02392351 about?

NCT02392351 is a clinical study titled "Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension (REDUCE HTN:REINFORCE)". The REDUCE HTN: REINFORCE study is being conducted to determine whether the Vessix Reduce™ Catheter and Vessix™ Generator for the treatment of uncontrolled hypertension (off-treatment office systolic blood pressure ≥150 mmHg and ≤180 mmHg) shows acceptable performance at 8 weeks when compared to a m...

What is the current status of trial NCT02392351?

This trial is currently completed. It is a NA study. The enrollment target is 51 participants. The study started on 2015-04. Estimated completion is 2019-08-02.

What interventions are being tested in trial NCT02392351?

The interventions under investigation include: Renal Denervation (Vessix) (DEVICE), Renal Angiography (DEVICE).

Who is sponsoring clinical trial NCT02392351?

This trial is sponsored by Boston Scientific Corporation, which has 280 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02392351's enrollment target sits among peer trials

51 1279th of 2000 higher than 722 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02701153 · 51 participants · NA

    Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

  • NCT03663790 · 51 participants · NA

    Effects of Gait Retraining on Lower Extremity Biomechanics

  • NCT03874052 · 51 participants · Phase 1

    Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

  • NCT04704661 · 51 participants · Phase 1

    Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02392351, the US trial registry maintained by the National Library of Medicine. NCT02392351 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.