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NCT02389127 · ClinicalTrials.gov registry record

Relationship Between HbA1c and Chronic Glycemia in Patients With Cirrhosis

A clinical trial, sponsored by University of Arkansas.

Completed
Registry status
50
Enrollment target

NCT02389127 is a clinical trial that has completed, run by University of Arkansas. The registered enrollment target is 50 participants.

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The verdict

NCT02389127 has completed, sponsored by University of Arkansas.

COMPLETED
Registry status
50 participants
Enrollment target

Study Summary

Cirrhosis and advanced liver disease have been associated with an increased risk for hyperglycemia and type 2 diabetes mellitus (T2DM). The diagnostic yield of common tests used to define diabetes and insulin resistance in the general population differs significantly from the one observed in patients with liver disease. Glycosylated hemoglobin A1c (HbA1c), a reliable test to assess chronic glycemia and recommended both for the diagnosis and monitoring of T2DM, is neither accurate nor reliable in patients with cirrhosis. A validation study has not been performed to define its true usefulness in the setting of cirrhosis. The study aims to determine the level of HbA1c that better corresponds to the diagnosis of T2DM - as determined by an oral glucose tolerance test (OGTT) - and to correlate the levels of HbA1c with the average glucose over a 12-week period in patients with cirrhosis and known T2DM, in cirrhotic patients with different degrees of liver impairment as compared to patients with T2DM and no liver disease.

Interventions

  • DEVICE Continuous glucose monitor (Dexcom, San Diego, CA)

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2015-07
Est. Completion 2017-06-01

Sponsor

University of Arkansas

318 total trials

What the Registry Record Tells You About NCT02389127

The ClinicalTrials.gov registry entry for NCT02389127 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arkansas, which has 318 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Continuous glucose monitor (Dexcom, San Diego, CA) is the first listed.

NCT02389127 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02389127 about?

NCT02389127 is a clinical study titled "Relationship Between HbA1c and Chronic Glycemia in Patients With Cirrhosis". Cirrhosis and advanced liver disease have been associated with an increased risk for hyperglycemia and type 2 diabetes mellitus (T2DM). The diagnostic yield of common tests used to define diabetes and insulin resistance in the general population differs significantly from the one observed in patient...

What is the current status of trial NCT02389127?

This trial is currently completed. The enrollment target is 50 participants. The study started on 2015-07. Estimated completion is 2017-06-01.

What interventions are being tested in trial NCT02389127?

The interventions under investigation include: Continuous glucose monitor (Dexcom, San Diego, CA) (DEVICE).

Who is sponsoring clinical trial NCT02389127?

This trial is sponsored by University of Arkansas, which has 318 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.