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NCT02367833 · ClinicalTrials.gov registry record · Phase 4
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis
A Phase 4 study, sponsored by Penn State University.
- Completed
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
NCT02367833: Completed Phase 4 study, sponsored by Penn State University.
NCT02367833 is a Phase 4 study that has completed, run by Penn State University. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02367833, a Phase 4 study, has completed, sponsored by Penn State University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study will determine whether the negative effects of combined oral contraceptive (COC) therapy on the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and bone turnover are dependent on the route of administration such that an attenuation of these effects is observed when a comparable dose of non-oral transdermal contraceptive (TDC) and contraceptive vaginal ring therapy (CVR) are also tested.
Primary Outcome
Changes in serially-sampled fasting serum concentrations of insulin-like growth factor-1 (IGF-1) before and after 49 days of contraceptive therapy. Data were only collected for IGF-1 levels, no assays were performed for IGFBP-1, IGFBP-3, and acid labile subunit (ALS) and no raw data were collected due to insufficient funds.
Interventions
- DRUG Combined Oral Contraceptive
- DRUG Transdermal Contraceptive
- DRUG Contraceptive Vaginal Ring
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2015-01 |
| Est. Completion | 2018-12 |
| Phase | Phase 4 |
What the finished NCT02367833 record still lists
NCT02367833 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 3 interventions - of which Combined Oral Contraceptive is the first listed.
NCT02367833 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02367833 about?
NCT02367833 is a clinical study titled "Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis". This study will determine whether the negative effects of combined oral contraceptive (COC) therapy on the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and bone turnover are dependent on the route of administration such that an attenuation of these effects is observed when a comparabl...
What is the current status of trial NCT02367833?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2015-01. Estimated completion is 2018-12.
What interventions are being tested in trial NCT02367833?
The interventions under investigation include: Combined Oral Contraceptive (DRUG), Transdermal Contraceptive (DRUG), Contraceptive Vaginal Ring (DRUG).
Who is sponsoring clinical trial NCT02367833?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02367833's enrollment target sits among peer trials
60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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