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NCT02367482 · ClinicalTrials.gov registry record
Tryptophan Metabolism in Human Brain Tumors-Novocure
A clinical trial, sponsored by Wayne State University.
- Completed
- Registry status
- 20
- Enrollment target
NCT02367482: Completed study, sponsored by Wayne State University.
NCT02367482 is a clinical trial that has completed, run by Wayne State University. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02367482 has completed, sponsored by Wayne State University.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
In this research study, we will track the build-up of tryptophan, a radioactive tracer, in the brain using positron emission tomography (PET) scanning. Tryptophan, in its natural state, is an amino acid (one of the building blocks of proteins) that is normally present in the brain, and is used by the brain cells to create various other compounds. This process is altered in the presence of a brain tumor. By using a form of tryptophan marked with a small amount of radiation, we will be able to track this process during the course of the PET scan. This research will help determine if AMT PET is a useful method to recognize and differentiate between various types of brain tumors. In addition, to study the mechanisms of altered tryptophan uptake in the tumor and brain, we will also measure tryptophan levels and related molecules in your blood (obtained as a part of the PET procedure) and tumor tissue (in case you will have surgery to remove the tumor). This will help us to find new approaches to treat brain tumors in the future by altering abnormal tryptophan metabolism.
Primary Outcome
To measure interval changes of tumoral metabolism, blood flow, and metabolites (NAA, choline, creatine, lipid, lactate) using AMT-PET, perfusion MRI, and 1H-MRS, respectively, in patients with recurrent GBM treated with NovoTTF.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-07 |
| Est. Completion | 2023-12-31 |
What the finished NCT02367482 record still lists
NCT02367482 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02367482 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02367482 about?
NCT02367482 is a clinical study titled "Tryptophan Metabolism in Human Brain Tumors-Novocure". In this research study, we will track the build-up of tryptophan, a radioactive tracer, in the brain using positron emission tomography (PET) scanning. Tryptophan, in its natural state, is an amino acid (one of the building blocks of proteins) that is normally present in the brain, and is used by th...
What is the current status of trial NCT02367482?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2014-07. Estimated completion is 2023-12-31.
Who is sponsoring clinical trial NCT02367482?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
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