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NCT02353026 · ClinicalTrials.gov registry record · Phase 1

Phase I Study of Intravenous Artesunate for Solid Tumors

A Phase 1 study, sponsored by Georgetown University.

Completed
Registry status
Phase 1
Development phase
19
Enrollment target

NCT02353026: Completed Phase 1 study, sponsored by Georgetown University.

NCT02353026 is a Phase 1 study that has completed, run by Georgetown University. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02353026, a Phase 1 study, has completed, sponsored by Georgetown University.

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

This is a Phase One study to determine the safety, tolerability, and maximum tolerated dose of intravenous artesunate in patients with solid tumors. A rapid dose escalation design will be used, in which single patients will be enrolled to escalating dose levels until a grade 2 or higher toxicity occurs during cycle 1. Enrollment will then continue using 3 to 6 patients at each dose level until a dose is reached at which 2 or more patients out of 6 experience a treatment-related toxicity.

Primary Outcome

One dose level below the dose at which 2 or more out of 6 patients experienced dose-limiting toxicities

Interventions

  • DRUG Intravenous Artesunate

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2015-01
Est. Completion 2015-12
Phase Phase 1
Georgetown University

227 total trials

What the finished NCT02353026 record still lists

NCT02353026 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).

The record links to 0 conditions, and to 1 intervention - of which Intravenous Artesunate is the first listed.

NCT02353026 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02353026 about?

NCT02353026 is a clinical study titled "Phase I Study of Intravenous Artesunate for Solid Tumors". This is a Phase One study to determine the safety, tolerability, and maximum tolerated dose of intravenous artesunate in patients with solid tumors. A rapid dose escalation design will be used, in which single patients will be enrolled to escalating dose levels until a grade 2 or higher toxicity occ...

What is the current status of trial NCT02353026?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2015-01. Estimated completion is 2015-12.

What interventions are being tested in trial NCT02353026?

The interventions under investigation include: Intravenous Artesunate (DRUG).

Who is sponsoring clinical trial NCT02353026?

This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02353026's enrollment target sits among peer trials

19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02353026, the US trial registry maintained by the National Library of Medicine. NCT02353026 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.