Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02348515 · ClinicalTrials.gov registry record
Cardiovascular Disease Protection Tissue
A clinical trial, sponsored by University of Florida.
- Completed
- Registry status
- 8
- Enrollment target
NCT02348515 is a clinical trial that has completed, run by University of Florida. The registered enrollment target is 8 participants.
The verdict
NCT02348515 has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- 8 participants
- Enrollment target
Study Summary
Recent evidence of a potential role for cardiac progenitor cells (CPCs) in cardiac repair and the discovery of a vasoprotective axis of the renin-angiotensin system (RAS) offer such breakthroughs. Investigators have observed that an imbalance in the vasoprotective axis {angiotensin converting enzyme 2 (ACE2)/angiotensin-(1-7) \[Ang-(1-7)\]/Mas receptor} and the vasodeleterious axis \[angiotensin converting enzyme (ACE)/angiotensin II (AngII)/AngII type 1 receptor (AT1R)\] of the RAS within the CPCs affects their functionality and regenerative potential. Investigators believe that restoring the balance between these two axes of the RAS is essential to improve CPC function and enhance their reparative capabilities. These observations have led to the hypothesis that genetic modification of CPCs by overexpression of ACE2/Ang-(1-7) will enhance their reparative function and improve their potential to attenuate myocardial ischemia-induced cardiac damage.
Interventions
- PROCEDURE Blood Draw
- PROCEDURE Heart failure or coronary disease
- PROCEDURE Heart transplant patients
- PROCEDURE Orthotopic Heart Transplant Patients
- PROCEDURE Heart Surgery Patients
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2013-06 |
| Est. Completion | 2018-09-28 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02348515
The ClinicalTrials.gov registry entry for NCT02348515 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Blood Draw is the first listed.
NCT02348515 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02348515 about?
NCT02348515 is a clinical study titled "Cardiovascular Disease Protection Tissue". Recent evidence of a potential role for cardiac progenitor cells (CPCs) in cardiac repair and the discovery of a vasoprotective axis of the renin-angiotensin system (RAS) offer such breakthroughs. Investigators have observed that an imbalance in the vasoprotective axis {angiotensin converting enzyme...
What is the current status of trial NCT02348515?
This trial is currently completed. The enrollment target is 8 participants. The study started on 2013-06. Estimated completion is 2018-09-28.
What interventions are being tested in trial NCT02348515?
The interventions under investigation include: Blood Draw (PROCEDURE), Heart failure or coronary disease (PROCEDURE), Heart transplant patients (PROCEDURE), Orthotopic Heart Transplant Patients (PROCEDURE), Heart Surgery Patients (PROCEDURE).
Who is sponsoring clinical trial NCT02348515?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.