Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02318329 · ClinicalTrials.gov registry record · Phase 1

Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors

A Phase 1 study of Gastric Cancer and Advanced Solid Tumors, sponsored by Five Prime Therapeutics.

Completed
Registry status
Phase 1
Development phase
79
Enrollment target
20
Study locations

NCT02318329 is a Phase 1 study of Gastric Cancer and Advanced Solid Tumors that has completed, run by Five Prime Therapeutics. The registered enrollment target is 79 participants, below the 319-participant average among 153 other Gastric Cancer trials with a reported enrollment target (75% lower). The trial reports 20 study locations across 10 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02318329, a Phase 1 study of Gastric Cancer and Advanced Solid Tumors, has completed, sponsored by Five Prime Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
79 participants
Enrollment target
20
Study locations

Study Summary

This is a three-part, open-label, safety, tolerability, and PK study of FPA144. Patients will be enrolled in Part 1 (A or B, dose escalation) or Part 2 (dose expansion) of the study, but not both.

Interventions

  • DRUG FPA144

Study Locations (20)

Other

  • Seoul National University Bundang Hospital - Seongnam-si
  • Seoul National University Hospital - Seoul
  • Severance Hospital, Yonsei University - Seoul
  • Samsung Medical Center - Seoul
  • Gangnam Severance Hospital - Seoul
  • Korea University Anam Hospital - Seoul

California

  • City of Hope Comprehensive Cancer Center - Duarte
  • Ronald Reagan UCLA Medical Center - Los Angeles
  • UCSF Helen Diller Family Comprehensive Cancer Center, Mission Bay - San Francisco
  • Innovative Cancer Research Institute - Whittier

Tennessee

  • Sarah Cannon Research Institute, LLC - Nashville
  • Vanderbilt University Medical Center - Nashville

Texas

  • The University of Texas M.D. Anderson Cancer Center - Houston
  • South Texas Accelerated Research Therapeutics, LLC - San Antonio

Illinois

  • The University of Chicago Medical Center - Chicago

Massachusetts

  • Dana-Farber Cancer Institute - Boston

Michigan

  • Karmanos Cancer Institute - Detroit

New York

  • Weill Cornell Medical Center - New York

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2014-11
Est. Completion 2019-06-30
Phase Phase 1

Sponsor

Five Prime Therapeutics

7 total trials

What the Registry Record Tells You About NCT02318329

The ClinicalTrials.gov registry entry for NCT02318329 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 79 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 319-participant average among 153 other Gastric Cancer trials with a reported enrollment target (75% lower). The listed sponsor is Five Prime Therapeutics, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Gastric Cancer appearing as the primary indexed condition, and to 1 intervention - of which FPA144 is the first listed.

NCT02318329 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Other, California, Tennessee.

Frequently Asked Questions

What is clinical trial NCT02318329 about?

NCT02318329 is a clinical study titled "Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors". This is a three-part, open-label, safety, tolerability, and PK study of FPA144. Patients will be enrolled in Part 1 (A or B, dose escalation) or Part 2 (dose expansion) of the study, but not both.

What is the current status of trial NCT02318329?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 79 participants. The study started on 2014-11. Estimated completion is 2019-06-30.

What conditions does trial NCT02318329 study?

This clinical trial studies the following conditions: Gastric Cancer, Advanced Solid Tumors, Transitional Cell Carcinoma of the Bladder.

What interventions are being tested in trial NCT02318329?

The interventions under investigation include: FPA144 (DRUG).

Who is sponsoring clinical trial NCT02318329?

This trial is sponsored by Five Prime Therapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02318329 being conducted?

This trial has 20 study locations across California, Illinois, Massachusetts, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Gastric Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.