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NCT02316379 · ClinicalTrials.gov registry record · Phase 1

Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

A Phase 1 study of Respiratory Disorders, sponsored by Children's Hospital Medical Center, Cincinnati.

Recruiting
Registry status
Phase 1
Development phase
100
Enrollment target
1
Study location

NCT02316379: Recruiting Phase 1 study of Respiratory Disorders, sponsored by Children's Hospital Medical Center, Cincinnati.

NCT02316379 is a Phase 1 study of Respiratory Disorders that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 100 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02316379, a Phase 1 study of Respiratory Disorders, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.

RECRUITING
Registry status
Phase 1
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.

Primary Outcome

quantify the measurement agreement between the ventilated volume of healthy lungs predicted via 129 Xe MRI and the ventilated volume of the pleural cavity predicted via proton MRI

Conditions Studied

Interventions

  • DEVICE MRI
  • DRUG Hyperpolarized 129 Xenon

Study Locations (1)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2015-02
Est. Completion 2031-08-24
Phase Phase 1

What NCT02316379 shows while recruiting

NCT02316379 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher).

The record links to 1 condition, with Respiratory Disorders appearing as the primary indexed condition, and to 2 interventions - of which MRI is the first listed.

NCT02316379 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT02316379 about?

NCT02316379 is a clinical study titled "Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration". The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.

What is the current status of trial NCT02316379?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2015-02. Estimated completion is 2031-08-24.

What conditions does trial NCT02316379 study?

This clinical trial studies the following conditions: Respiratory Disorders.

What interventions are being tested in trial NCT02316379?

The interventions under investigation include: MRI (DEVICE), Hyperpolarized 129 Xenon (DRUG).

Who is sponsoring clinical trial NCT02316379?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02316379 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Respiratory Disorders

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02316379's enrollment target sits among peer trials

100 547th of 2000 higher than 1,411 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02316379, the US trial registry maintained by the National Library of Medicine. NCT02316379 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.