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NCT02310568 · ClinicalTrials.gov registry record · Phase 2

POC Study in Partially Responsive Generalized Anxiety Disorder

A Phase 2 study, sponsored by Pfizer.

Terminated
Registry status
Phase 2
Development phase
90
Enrollment target

NCT02310568: Clinical Trial Phase 2 study, sponsored by Pfizer.

NCT02310568 is a Phase 2 study that was terminated before completion, run by Pfizer. The registered enrollment target is 90 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02310568, a Phase 2 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 2
Development phase
90 participants
Enrollment target

Study Summary

This study aims to evaluate whether PF-06372865 is safe and effective in the treatment of sub-optimally controlled symptoms of generalized anxiety disorder during two 4-week treatment periods using a Sequential Parallel Comparison Design (SPCD). The study will use the Hamilton Anxiety Rating Scale (HAM-A) to measure change in symptoms from baseline for two doses of PF-06372865 compared to placebo.

Primary Outcome

The HAM-A scale was a clinician rated interview scale designed to measure the signs and symptoms of anxiety. It had 14-items to rate the intensity of psychic and somatic anxiety on a 5-point severity scale. Each item ranging from 0 (not present) to 4 (very severe) were summed up to give a total possible score of 0 (not present) to 56 (very severe), where lower scores indicates less anxiety.

Interventions

  • DRUG PF-06372865.

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2014-11
Est. Completion 2015-10
Phase Phase 2
Pfizer

1,845 total trials

Why NCT02310568 stopped before completion

NCT02310568 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower).

The record links to 0 conditions, and to 1 intervention - of which PF-06372865. is the first listed.

NCT02310568 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02310568 about?

NCT02310568 is a clinical study titled "POC Study in Partially Responsive Generalized Anxiety Disorder". This study aims to evaluate whether PF-06372865 is safe and effective in the treatment of sub-optimally controlled symptoms of generalized anxiety disorder during two 4-week treatment periods using a Sequential Parallel Comparison Design (SPCD). The study will use the Hamilton Anxiety Rating Scale (...

What is the current status of trial NCT02310568?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2014-11. Estimated completion is 2015-10.

What interventions are being tested in trial NCT02310568?

The interventions under investigation include: PF-06372865. (DRUG).

Who is sponsoring clinical trial NCT02310568?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02310568's enrollment target sits among peer trials

90 772nd of 2000 higher than 1,199 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02310568, the US trial registry maintained by the National Library of Medicine. NCT02310568 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.