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NCT02301663 · ClinicalTrials.gov registry record · NA
Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease
A NA study of Microvascular Coronary Dysfunction, sponsored by Cedars-Sinai Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT02301663: Recruiting NA study of Microvascular Coronary Dysfunction, sponsored by Cedars-Sinai Medical Center.
NCT02301663 is a NA study of Microvascular Coronary Dysfunction that is actively recruiting participants, run by Cedars-Sinai Medical Center. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02301663, a NA study of Microvascular Coronary Dysfunction, is actively recruiting participants, sponsored by Cedars-Sinai Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Microvascular coronary dysfunction (MCD) (abnormities in small blood vessels/arteries in heart) with symptoms of persistent chest pain, primarily impacts women. There are an estimated 2-3 million women in the US with MCD and about 100,000 new cases annually. Recent data from our research group suggests that coronary microvascular disease impairs the way the heart relaxes. This pilot study will attempt to exacerbate this phenotype in an effort to better understand the pathophysiology of the disease. The investigators will recruit 30 volunteers total (10 healthy calibration subjects, 10 women with microvascular disease, and 10 age-match women for the group with microvascular disease). Subjects will undergo a series of "stress" maneuvers in conjunction with advanced cardiac magnetic resonance imaging.
Conditions Studied
Interventions
- OTHER Handgrip
- OTHER Altitude simulation
- OTHER Leg exercise
Study Locations (1)
California
- Cedars-Sinai Medical Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2014-11 |
| Est. Completion | 2030-12 |
| Phase | NA |
What NCT02301663 shows while recruiting
NCT02301663 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Microvascular Coronary Dysfunction appearing as the primary indexed condition, and to 3 interventions - of which Handgrip is the first listed.
NCT02301663 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT02301663 about?
NCT02301663 is a clinical study titled "Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease". Microvascular coronary dysfunction (MCD) (abnormities in small blood vessels/arteries in heart) with symptoms of persistent chest pain, primarily impacts women. There are an estimated 2-3 million women in the US with MCD and about 100,000 new cases annually. Recent data from our research group sugge...
What is the current status of trial NCT02301663?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2014-11. Estimated completion is 2030-12.
What conditions does trial NCT02301663 study?
This clinical trial studies the following conditions: Microvascular Coronary Dysfunction.
What interventions are being tested in trial NCT02301663?
The interventions under investigation include: Handgrip (OTHER), Altitude simulation (OTHER), Leg exercise (OTHER).
Who is sponsoring clinical trial NCT02301663?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02301663 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02301663's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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