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NCT02299414 · ClinicalTrials.gov registry record · Phase 4

Chronic Hypertension and Pregnancy (CHAP) Project

A Phase 4 study, sponsored by University of Alabama at Birmingham.

Completed
Registry status
Phase 4
Development phase
2,408
Enrollment target

NCT02299414: Completed Phase 4 study, sponsored by University of Alabama at Birmingham.

NCT02299414 is a Phase 4 study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 2,408 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (365% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02299414, a Phase 4 study, has completed, sponsored by University of Alabama at Birmingham.

COMPLETED
Registry status
Phase 4
Development phase
2,408 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate whether a blood pressure treatment strategy during pregnancy to achieve targets that are recommended for non-pregnant reproductive-age adults (\<140/90 mmHg) compared ACOG- recommended standard during pregnancy (no treatment unless BP is severe) is effective and safe.

Primary Outcome

One or more severe outcomes including fetal death or neonatal death up to discharge or 90 days if prior; preeclampsia with severe features up to 2 weeks postpartum (Severe hypertension and proteinuria or hypertension and severe features per ACOG); placental abruption; or indicated PTB \<35 weeks (not due to spontaneous preterm labor or membrane rupture).

Interventions

  • DRUG Anti-hypertensive therapy
  • OTHER No anti-hypertensive therapy (unless BP is severe)

Trial Details

FieldValue
Enrollment Target 2,408 participants
Start Date 2015-06
Est. Completion 2022-12-16
Phase Phase 4
University of Alabama at Birmingham

1,160 total trials

What the finished NCT02299414 record still lists

NCT02299414 is an interventional study that assigns participants to a tested intervention. Its 2,408 participants enrollment target places it among the larger protocols in the corpus, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (365% higher).

The record links to 0 conditions, and to 2 interventions - of which Anti-hypertensive therapy is the first listed.

NCT02299414 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02299414 about?

NCT02299414 is a clinical study titled "Chronic Hypertension and Pregnancy (CHAP) Project". The purpose of this study is to evaluate whether a blood pressure treatment strategy during pregnancy to achieve targets that are recommended for non-pregnant reproductive-age adults (\<140/90 mmHg) compared ACOG- recommended standard during pregnancy (no treatment unless BP is severe) is effective ...

What is the current status of trial NCT02299414?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 2,408 participants. The study started on 2015-06. Estimated completion is 2022-12-16.

What interventions are being tested in trial NCT02299414?

The interventions under investigation include: Anti-hypertensive therapy (DRUG), No anti-hypertensive therapy (unless BP is severe) (OTHER).

Who is sponsoring clinical trial NCT02299414?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02299414's enrollment target sits among peer trials

2,408 30th of 2000 higher than 1,971 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02299414, the US trial registry maintained by the National Library of Medicine. NCT02299414 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.