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COMPLETED Phase 3

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis

NCT02294227 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study was to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, safety and tolerability up to 2 years in subjects with active PsA despite current or previous NSAID or DMARD therapy

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL Secukinumab

Study Locations (20)

Florida

  • Novartis Investigative Site — Palm Harbor
  • Novartis Investigative Site — Sarasota

South Carolina

  • Novartis Investigative Site — Charleston
  • Novartis Investigative Site — Greenville

Washington

  • Novartis Investigative Site — Seattle
  • Novartis Investigative Site — Seattle

Arizona

  • Novartis Investigative Site — Mesa

California

  • Novartis Investigative Site — Upland

Colorado

  • Novartis Investigative Site — Denver

Illinois

  • Novartis Investigative Site — Peoria

Louisiana

  • Novartis Investigative Site — Shreveport

Trial Details

FieldValue
Enrollment Target 341 participants
Start Date 2015-05-29
Est. Completion 2017-12-19
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

792 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02294227

The ClinicalTrials.gov registry entry for NCT02294227 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 341 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02294227 reports 20 study locations spanning 17 distinct geographic areas — top geographies include Florida, South Carolina, Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02294227 about?

NCT02294227 is a clinical study titled "16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis". The purpose of this study was to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, s...

What is the current status of trial NCT02294227?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 341 participants. The study started on 2015-05-29. Estimated completion is 2017-12-19.

What conditions does trial NCT02294227 study?

This clinical trial studies the following conditions: Arthritis, Psoriatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02294227?

The interventions under investigation include: Placebo (OTHER), Secukinumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02294227?

This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02294227 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial