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NCT02294227 · ClinicalTrials.gov registry record · Phase 3

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis

A Phase 3 study of Arthritis, Psoriatic, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
341
Enrollment target
20
Study locations

NCT02294227 is a Phase 3 study of Arthritis, Psoriatic that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 341 participants, below the 555-participant average among 16 other Arthritis, Psoriatic trials with a reported enrollment target (39% lower). The trial reports 20 study locations across 17 states.

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The verdict

NCT02294227, a Phase 3 study of Arthritis, Psoriatic, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
341 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study was to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, safety and tolerability up to 2 years in subjects with active PsA despite current or previous NSAID or DMARD therapy

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL Secukinumab

Study Locations (20)

Florida

  • Novartis Investigative Site - Palm Harbor
  • Novartis Investigative Site - Sarasota

South Carolina

  • Novartis Investigative Site - Charleston
  • Novartis Investigative Site - Greenville

Washington

  • Novartis Investigative Site - Seattle
  • Novartis Investigative Site - Seattle

Arizona

  • Novartis Investigative Site - Mesa

California

  • Novartis Investigative Site - Upland

Colorado

  • Novartis Investigative Site - Denver

Illinois

  • Novartis Investigative Site - Peoria

Louisiana

  • Novartis Investigative Site - Shreveport

Trial Details

FieldValue
Enrollment Target 341 participants
Start Date 2015-05-29
Est. Completion 2017-12-19
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT02294227

The ClinicalTrials.gov registry entry for NCT02294227 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 341 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 555-participant average among 16 other Arthritis, Psoriatic trials with a reported enrollment target (39% lower). The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02294227 reports 20 study locations spanning 17 distinct geographic areas - top geographies include Florida, South Carolina, Washington.

Frequently Asked Questions

What is clinical trial NCT02294227 about?

NCT02294227 is a clinical study titled "16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis". The purpose of this study was to provide 16-week efficacy, safety and tolerability data versus placebo to support the use of secukinumab 150 mg by subcutaneous (s.c.) self-administration with or without a loading regimen and maintenance dosing using pre-filled syringe (PFS) and to assess efficacy, s...

What is the current status of trial NCT02294227?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 341 participants. The study started on 2015-05-29. Estimated completion is 2017-12-19.

What conditions does trial NCT02294227 study?

This clinical trial studies the following conditions: Arthritis, Psoriatic.

What interventions are being tested in trial NCT02294227?

The interventions under investigation include: Placebo (OTHER), Secukinumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02294227?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02294227 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.