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NCT02292225 · ClinicalTrials.gov registry record · Phase 1

Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)

A Phase 1 study, sponsored by SecuraBio.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT02292225: Clinical Trial Phase 1 study, sponsored by SecuraBio.

NCT02292225 is a Phase 1 study that was terminated before completion, run by SecuraBio. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02292225, a Phase 1 study, was terminated before completion, sponsored by SecuraBio.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

To evaluate the safety, pharmacokinetics, and pharmacodynamics of Duvelisib (IPI-145) in combination with obinutuzumab in patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma previously treated with a BTKi.

Interventions

  • DRUG Obinutuzumab
  • DRUG IPI-145 (duvelisib)

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2015-02
Est. Completion 2016-11
Phase Phase 1
SecuraBio

15 total trials

Why NCT02292225 stopped before completion

NCT02292225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Obinutuzumab is the first listed.

NCT02292225 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02292225 about?

NCT02292225 is a clinical study titled "Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)". To evaluate the safety, pharmacokinetics, and pharmacodynamics of Duvelisib (IPI-145) in combination with obinutuzumab in patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma previously treated with a BTKi.

What is the current status of trial NCT02292225?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2015-02. Estimated completion is 2016-11.

What interventions are being tested in trial NCT02292225?

The interventions under investigation include: Obinutuzumab (DRUG), IPI-145 (duvelisib) (DRUG).

Who is sponsoring clinical trial NCT02292225?

This trial is sponsored by SecuraBio, which has 15 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02292225's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02292225, the US trial registry maintained by the National Library of Medicine. NCT02292225 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.