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NCT02285270 · ClinicalTrials.gov registry record · NA

Circadian Brown Adipose Tissue Metabolism

A NA study, sponsored by University of Pennsylvania.

Completed
Registry status
NA
Development phase
10
Enrollment target

NCT02285270: Completed NA study, sponsored by University of Pennsylvania.

NCT02285270 is a NA study that has completed, run by University of Pennsylvania. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02285270, a NA study, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

Brown adipose tissue is poorly understood fat that can metabolize glucose in order to generate heat. Since activated brown fat has a high metabolic rate, it is of great interest as a potential target to combat obesity. However, the signaling and control of brown fat metabolism is poorly understood. Because brown fat uses glucose as its energy source, brown fat metabolism can be imaged with PET/CT using the positron emitting glucose analog F-18 FDG. We have recently shown in mice a striking circadian variation in brown fat metabolism as evidenced by changes in FDG uptake. In this study we endeavor to generate pilot data on a potential circadian variation in brown fat activation in healthy humans.

Interventions

  • DEVICE FDG PET/CT

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2014-03
Est. Completion 2015-04
Phase NA
University of Pennsylvania

1,423 total trials

What the finished NCT02285270 record still lists

NCT02285270 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which FDG PET/CT is the first listed.

NCT02285270 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02285270 about?

NCT02285270 is a clinical study titled "Circadian Brown Adipose Tissue Metabolism". Brown adipose tissue is poorly understood fat that can metabolize glucose in order to generate heat. Since activated brown fat has a high metabolic rate, it is of great interest as a potential target to combat obesity. However, the signaling and control of brown fat metabolism is poorly understood. ...

What is the current status of trial NCT02285270?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2014-03. Estimated completion is 2015-04.

What interventions are being tested in trial NCT02285270?

The interventions under investigation include: FDG PET/CT (DEVICE).

Who is sponsoring clinical trial NCT02285270?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02285270's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02285270, the US trial registry maintained by the National Library of Medicine. NCT02285270 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.