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NCT02279160 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension
A Phase 2 study, sponsored by United Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 61
- Enrollment target
NCT02279160: Completed Phase 2 study, sponsored by United Therapeutics.
NCT02279160 is a Phase 2 study that has completed, run by United Therapeutics. The registered enrollment target is 61 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02279160, a Phase 2 study, has completed, sponsored by United Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 61 participants
- Enrollment target
Study Summary
The study was conducted as a placebo-controlled, randomized, 22-week double-blind study which included a dose titration period. An additional transition period occurred for those patients who elected to enroll into the open-label extension study, APD811-007. A total of 61 patients with PAH were enrolled.
Primary Outcome
Measurements of PVR from right heart catheterization were obtained prior to Day 1 of the dose titration period and at the end of the maintenance period (Week 22), approximately 4 hours after the last dose of study drug.
Interventions
- DRUG Placebo
- DRUG APD811
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2014-12 |
| Est. Completion | 2017-06 |
| Phase | Phase 2 |
What the finished NCT02279160 record still lists
NCT02279160 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02279160 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02279160 about?
NCT02279160 is a clinical study titled "Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension". The study was conducted as a placebo-controlled, randomized, 22-week double-blind study which included a dose titration period. An additional transition period occurred for those patients who elected to enroll into the open-label extension study, APD811-007. A total of 61 patients with PAH were enro...
What is the current status of trial NCT02279160?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 61 participants. The study started on 2014-12. Estimated completion is 2017-06.
What interventions are being tested in trial NCT02279160?
The interventions under investigation include: Placebo (DRUG), APD811 (DRUG).
Who is sponsoring clinical trial NCT02279160?
This trial is sponsored by United Therapeutics, which has 63 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02279160's enrollment target sits among peer trials
61 1026th of 2000 higher than 974 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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