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NCT02277522 · ClinicalTrials.gov registry record · Early Phase 1
CD19 Redirected Autologous T Cells for Hodgkin Lymphoma
A Early Phase 1 study, sponsored by University of Pennsylvania.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 4
- Enrollment target
NCT02277522: Clinical Trial Early Phase 1 study, sponsored by University of Pennsylvania.
NCT02277522 is a Early Phase 1 study that was terminated before completion, run by University of Pennsylvania. The registered enrollment target is 4 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02277522, a Early Phase 1 study, was terminated before completion, sponsored by University of Pennsylvania.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
Pilot open-label study to estimate the feasibility, safety and efficacy of intravenously administered, RNA electroporated autologous T cells expressing CD19 chimeric antigen receptors expressing tandem TCR and 4-1BB (TCR /4-1BB) costimulatory domains (referred to as RNA CART19) in Hodgkin Lymphoma (HL) patients.
Interventions
- BIOLOGICAL RNA anti-CD19 CAR T cells
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2014-10 |
| Est. Completion | 2017-06-27 |
| Phase | Early Phase 1 |
Why NCT02277522 stopped before completion
NCT02277522 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which RNA anti-CD19 CAR T cells is the first listed.
NCT02277522 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02277522 about?
NCT02277522 is a clinical study titled "CD19 Redirected Autologous T Cells for Hodgkin Lymphoma". Pilot open-label study to estimate the feasibility, safety and efficacy of intravenously administered, RNA electroporated autologous T cells expressing CD19 chimeric antigen receptors expressing tandem TCR and 4-1BB (TCR /4-1BB) costimulatory domains (referred to as RNA CART19) in Hodgkin Lymphoma (...
What is the current status of trial NCT02277522?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 4 participants. The study started on 2014-10. Estimated completion is 2017-06-27.
What interventions are being tested in trial NCT02277522?
The interventions under investigation include: RNA anti-CD19 CAR T cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT02277522?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02277522's enrollment target sits among peer trials
4 1921st of 2000 higher than 53 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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