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NCT02276066 · ClinicalTrials.gov registry record · NA
Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 73
- Enrollment target
NCT02276066 is a NA study that has completed, run by University of Florida. The registered enrollment target is 73 participants.
The verdict
NCT02276066, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 73 participants
- Enrollment target
Study Summary
This study investigates the mechanism by which kidney dysfunction perpetuates inflammation, immunosuppression, and catabolism (PICS) in chronic critical illness. The investigators will test the hypothesis that persistent kidney dysfunction in sepsis associated by chronic critical illness contributes to decreased survival through the development of PICS. In chronic critical illness, the persistence of the inflammatory state may lead to capillary rarefication in the kidney causing accelerated chronic kidney disease. Progression of chronic kidney disease during chronic critical illness can drive PICS. Indeed, many of the features of chronic critical illness are consistent with the protein-energy malnutrition and muscle wasting associated with chronic kidney disease. Thus, the kidney can play a contributory role in chronic critical illness and PICS.
Interventions
- DIAGNOSTIC_TEST Urine Collection
- DIAGNOSTIC_TEST GFR by Iohexol
- DIAGNOSTIC_TEST Blood samples
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2015-02 |
| Est. Completion | 2023-05-20 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02276066
The ClinicalTrials.gov registry entry for NCT02276066 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Urine Collection is the first listed.
NCT02276066 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02276066 about?
NCT02276066 is a clinical study titled "Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS". This study investigates the mechanism by which kidney dysfunction perpetuates inflammation, immunosuppression, and catabolism (PICS) in chronic critical illness. The investigators will test the hypothesis that persistent kidney dysfunction in sepsis associated by chronic critical illness contributes...
What is the current status of trial NCT02276066?
This trial is currently completed. It is a NA study. The enrollment target is 73 participants. The study started on 2015-02. Estimated completion is 2023-05-20.
What interventions are being tested in trial NCT02276066?
The interventions under investigation include: Urine Collection (DIAGNOSTIC_TEST), GFR by Iohexol (DIAGNOSTIC_TEST), Blood samples (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT02276066?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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