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NCT02268461 · ClinicalTrials.gov registry record · NA
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT02268461: Completed NA study, sponsored by University of Minnesota.
NCT02268461 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02268461, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Spasticity is a common complication of stroke affecting quality of life. Spasticity involves exaggerated stretch reflexes that create stiffness in muscles with associated loss of motion and functional control. Traditional treatments involve range of motion, medications, and sometimes surgery. Each of these has its own limitations, which has invited exploration of alternative modes of treatment. One such treatment with the potential to benefit spasticity is repetitive Transcranial Magnetic Stimulation (rTMS). The purpose of this study is to determine whether patients with upper limb spasticity as a consequence of a chronic stroke can benefit from stimulation of the non-affected hemisphere of the brain with low-frequency (inhibitory) repetitive Transcranial Magnetic Stimulation (rTMS), potentially leading to a reduction of spasticity and clinical improvement in upper limb function.
Primary Outcome
Motor evoked potentials (MEPs) were measured using surface EMG. The average amplitude of 10 MEPs measured at baseline was compared to the average of 10 MEPs measured at post-test and this difference is recorded as the change in corticospinal excitability. A greater negative value would indicate larger post-test MEPs and increased corticospinal excitability.
Interventions
- DEVICE repetitive Transcranial Magnetic Stimulation (rTMS)
- DEVICE Sham repetitive Transcranial Magnetic Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2014-12 |
| Est. Completion | 2016-12 |
| Phase | NA |
What the finished NCT02268461 record still lists
NCT02268461 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.
NCT02268461 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02268461 about?
NCT02268461 is a clinical study titled "Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity". Spasticity is a common complication of stroke affecting quality of life. Spasticity involves exaggerated stretch reflexes that create stiffness in muscles with associated loss of motion and functional control. Traditional treatments involve range of motion, medications, and sometimes surgery. Each o...
What is the current status of trial NCT02268461?
This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2014-12. Estimated completion is 2016-12.
What interventions are being tested in trial NCT02268461?
The interventions under investigation include: repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE), Sham repetitive Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT02268461?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02268461's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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