Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02268448 · ClinicalTrials.gov registry record · Phase 1

Treatment of Chronic Itch in Atopic Dermatitis (Eczema): Nerve Function

A Phase 1 study, sponsored by University of Minnesota.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target

NCT02268448: Completed Phase 1 study, sponsored by University of Minnesota.

NCT02268448 is a Phase 1 study that has completed, run by University of Minnesota. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02268448, a Phase 1 study, has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and efficacy of oral clonidine in subjects with symptomatic atopic dermatitis and to assess the safety and efficacy of oral naltrexone in subjects with symptomatic atopic dermatitis.

Primary Outcome

Participants will take personal surveys regarding the reduction in itching after 3 months

Interventions

  • DRUG Naltrexone
  • DRUG Clonidine

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2015-07
Est. Completion 2022-09
Phase Phase 1
University of Minnesota

966 total trials

What the finished NCT02268448 record still lists

NCT02268448 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 2 interventions - of which Naltrexone is the first listed.

NCT02268448 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02268448 about?

NCT02268448 is a clinical study titled "Treatment of Chronic Itch in Atopic Dermatitis (Eczema): Nerve Function". The purpose of this study is to assess the safety and efficacy of oral clonidine in subjects with symptomatic atopic dermatitis and to assess the safety and efficacy of oral naltrexone in subjects with symptomatic atopic dermatitis.

What is the current status of trial NCT02268448?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2015-07. Estimated completion is 2022-09.

What interventions are being tested in trial NCT02268448?

The interventions under investigation include: Naltrexone (DRUG), Clonidine (DRUG).

Who is sponsoring clinical trial NCT02268448?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02268448's enrollment target sits among peer trials

8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02268448, the US trial registry maintained by the National Library of Medicine. NCT02268448 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.