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NCT02261753 · ClinicalTrials.gov registry record · NA
Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy
A NA study, sponsored by University College, London.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT02261753: Clinical Trial NA study, sponsored by University College, London.
NCT02261753 is a NA study that was terminated before completion, run by University College, London. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02261753, a NA study, was terminated before completion, sponsored by University College, London.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
The investigators are undertaking the first European Randomised Controlled Trial (RCT) for epilepsy surgery in children with FCD type II, to prospectively evaluate the role of the KD prior to surgery in improving seizure outcome. The investigators will evaluate the role of KD as a disease-modifying treatment to achieve seizure control and improve neurodevelopment and quality of life. Children age 3 - 15 years with pharmacoresistant epilepsy believed to be the result of focal cortical dysplasia type II, considered to be surgically treatable, will be randomised to either receive 6m treatment presurgery with a ketogenic diet, or to proceed direct to surgery (no pretreatment). Primary outcome will be the time to achieve a period of 6 months of seizure freedom from the date of randomisation. Tissue resected at surgery will also be evaluated with regard to the degree of any methylation of DNA.
Primary Outcome
the time to achieve a period of 6 months of seizure freedom from the date of randomisation pretreated KD group vs non pretreated group
Interventions
- DIETARY_SUPPLEMENT Classical ketogenic diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2014-10 |
| Est. Completion | 2017-07-26 |
| Phase | NA |
Why NCT02261753 stopped before completion
NCT02261753 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Classical ketogenic diet is the first listed.
NCT02261753 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02261753 about?
NCT02261753 is a clinical study titled "Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy". The investigators are undertaking the first European Randomised Controlled Trial (RCT) for epilepsy surgery in children with FCD type II, to prospectively evaluate the role of the KD prior to surgery in improving seizure outcome. The investigators will evaluate the role of KD as a disease-modifying ...
What is the current status of trial NCT02261753?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2014-10. Estimated completion is 2017-07-26.
What interventions are being tested in trial NCT02261753?
The interventions under investigation include: Classical ketogenic diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02261753?
This trial is sponsored by University College, London, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02261753's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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